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2-Pyrrolylethylamine

2-Pyrrolylethylamine
Clinical data
Other names2-(2-Pyrrolyl)ethylamine; NEA; 2-NEA
Identifiers
  • 2-(1H-pyrrol-2-yl)ethanamine
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC6H10N2
Molar mass110.160 g·mol−1
3D model (JSmol)
  • C1=CNC(=C1)CCN
  • InChI=1S/C6H10N2/c7-4-3-6-2-1-5-8-6/h1-2,5,8H,3-4,7H2
  • Key:IAZZNTYMXXEHHT-UHFFFAOYSA-N

2-Pyrrolylethylamine (NEA, 2-NEA, or 2-(2-pyrrolyl)ethylamine) is a chemical compound of the arylalkylamine family.[1]

It is related to other arylalkylamines as well as trace amines including tryptamine (2-indolylethylamine), phenethylamine (2-phenylethylamine), 2-furylethylamine, thiopropamine (1-(2-thienyl)-2-aminopropane), and isocyclamine (cyclopentanylaminopropane), among others.[1] Many of these compounds are monoamine releasing agents and/or reuptake inhibitors.[1]

NEA is known to be pharmacologically active itself, for instance having histamine-like activity on the isolated guinea pig ileum and having effects on gastric acid secretion in dogs.[1]

The compound was first described in the scientific literature by 1949.[1]

See also

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References

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  1. ^ a b c d e Shulgin A, Manning T, Daley PF (2011). "#67. FEA". The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds. Vol. 1. Berkeley, CA: Transform Press. pp. 138–141. ISBN 978-0-9630096-3-0. OCLC 709667010.


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