Acecarbromal
Names | |
---|---|
Preferred IUPAC name N-(Acetylcarbamoyl)-2-bromo-2-ethylbutanamide | |
Other names 1-Acetyl-3-(2-bromo-2-ethylbutyryl)urea | |
Identifiers | |
CAS Number |
|
3D model (JSmol) |
|
ChEMBL |
|
ChemSpider |
|
ECHA InfoCard | 100.000.953 |
EC Number |
|
KEGG |
|
MeSH | acecarbromal |
PubChem CID |
|
UNII |
|
CompTox Dashboard (EPA) |
|
InChI
| |
| |
Properties | |
Chemical formula | C9H15BrN2O3 |
Molar mass | 279.134 g·mol−1 |
Pharmacology | |
Routes of administration | Oral |
Legal status |
|
Related compounds | |
Related compounds |
|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Acecarbromal (INN) (brand names Sedamyl, Abasin, Carbased, Paxarel, Sedacetyl, numerous others), also known as acetylcarbromal and acetyladalin, is a hypnotic and sedative drug of the ureide (acylurea) group discovered by Bayer in 1917[1] that was formerly marketed in the United States and Europe.[2][3] It is also used in combination with extract of quebracho and vitamin E as a treatment for erectile dysfunction under the brand name Afrodor in Europe.[4][5][6] Acecarbromal is structurally related to the barbiturates, which are basically cyclized ureas.[7] Prolonged use is not recommended as it can cause bromine poisoning.[7]
See also
References
- ^ DE 327129, "Verfahren zur Darstellung von Derivaten bromacylierter Harnstoffe (Procedures for the preparation of derivatives of bromoacylated urea)", issued 5 October 1920, assigned to Bayer AG
- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 2–. ISBN 978-1-4757-2085-3.
- ^ Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 4–. ISBN 978-3-88763-075-1.
- ^ Muller NF, Dessing RP, eds. (19 June 1998). European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 36–. ISBN 978-3-7692-2114-5.
- ^ Baumbusch F, Papp GK, Kopa ZS (1995). "Treatment for potency problems with Afrodor 2000". Acta Chirurgica Hungarica. 35 (1–2): 87–92. PMID 8659243.
- ^ Sperling H, Lümmen G, Luboldt HJ, Rübben H (January 1999). "[Secondary erectile dysfunction. Is oral medication in the diagnostic phase indicated?]". Der Urologe. Ausg. A. 38 (1): 56–9. doi:10.1007/s001200050246. PMID 10081103. S2CID 24907635.
- ^ a b Williams DA, Foye WO, Lemke TL (January 2002). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 380–. ISBN 978-0-683-30737-5.
- v
- t
- e
Antihistamines | |
---|---|
Antidepressants | |
Antipsychotics |
Antidepressants | |
---|---|
Antipsychotics | |
Others |
- Agomelatine
- Melatonin
- Ramelteon
- Tasimelteon
- Cannabidiol
- Cannabis
- Chlorophenylalkyldiols
- Diethylpropanediol
- Evoxine
- Fenadiazole
- Guaifenesin-related muscle relaxants
- Midaflur
- Opioids (e.g., morphine)
- Passion flower
- Scopolamine
- Trazodone
- UMB68
- Valnoctamide
This sedative-related article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e