Amflutizole
Chemical compound
- none
- 4-Amino-3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-5-carboxylic acid
- 82114-19-0 Y
- 54833
- 49508 Y
- 83N680M457
- D02896 Y
- ChEMBL2106558
- DTXSID00868642
- Interactive image
- FC(F)(F)c1cccc(c1)c2nsc(c2N)C(=O)O
InChI
- InChI=1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18) Y
- Key:KVMCEGAWQYTFKC-UHFFFAOYSA-N Y
Amflutizole is a xanthine oxidase inhibitor[1] used for the treatment of gout.
References
- ^ O'Regan MH, Smith-Barbour M, Perkins LM, Cao X, Phillis JW (October 1994). "The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex". Neuropharmacology. 33 (10): 1197–201. doi:10.1016/S0028-3908(05)80010-3. PMID 7862255. S2CID 37262919.
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Purine receptor modulators
(ligands)
P0 (adenine) |
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P1 (adenosine) |
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P2 (nucleotide) |
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(blockers)
CNTsTooltip Concentrative nucleoside transporters |
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ENTsTooltip Equilibrative nucleoside transporters | |
PMATTooltip Plasma membrane monoamine transporter |
(inhibitors)
XOTooltip Xanthine oxidase | |
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Others |
See also: Receptor/signaling modulators
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