CARD16 |
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Identifiers |
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Aliases | CARD16, COP, COP1, PSEUDO-ICE, caspase recruitment domain family member 16, LLID-114769 |
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External IDs | OMIM: 615680; HomoloGene: 133086; GeneCards: CARD16; OMA:CARD16 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 11 (human)[1] |
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| Band | 11q22.3 | Start | 105,041,326 bp[1] |
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End | 105,101,431 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - monocyte
- granulocyte
- stromal cell of endometrium
- spleen
- appendix
- germinal epithelium
- bone marrow
- bone marrow cells
- mucosa of transverse colon
- superficial temporal artery
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| | More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - peptidase inhibitor activity
- protein binding
- kinase binding
- identical protein binding
- caspase binding
- CARD domain binding
- cysteine-type endopeptidase inhibitor activity
- cysteine-type endopeptidase activity
| Cellular component | - protease inhibitor complex
- protein-containing complex
| Biological process | - regulation of apoptotic process
- negative regulation of peptidase activity
- negative regulation of lipopolysaccharide-mediated signaling pathway
- negative regulation of protein binding
- positive regulation of NF-kappaB transcription factor activity
- inhibition of cysteine-type endopeptidase activity
- negative regulation of tumor necrosis factor-mediated signaling pathway
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
- cellular response to hypoxia
- cellular response to UV-C
- positive regulation of I-kappaB kinase/NF-kappaB signaling
- cellular response to lipopolysaccharide
- proteolysis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001017534 NM_052889 NM_001394580 |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 11: 105.04 – 105.1 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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