Denaverine
Chemical compound
- Gr 1 (Germany)
administration
- QG02CX90 (WHO)
- In general: ℞ (Prescription only)
37% (oral solution)
- 2-(Dimethylamino)ethyl (2-ethylbutoxy)diphenylacetate
- 3579-62-2
Y
3321-06-0 (hydrochloride)
- 71130
- 64278
N
- O14NF38MTL
- D07787
Y
- ChEMBL1614656
N
- DTXSID10189315
- Interactive image
- CCC(CC)COC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OCCN(C)C
- InChI=1S/C24H33NO3/c1-5-20(6-2)19-28-24(21-13-9-7-10-14-21,22-15-11-8-12-16-22)23(26)27-18-17-25(3)4/h7-16,20H,5-6,17-19H2,1-4H3
N
- Key:FPTOUQZVCUIPHY-UHFFFAOYSA-N
N
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Denaverine is an antispasmodic drug. It was developed in Germany and patented in 1974. Denaverine hydrochloride is used in veterinary medicine under the trade name Sensiblex as a muscle relaxant for the myometrium of cows and dogs during parturition.[1] Under the trade name Spasmalgan, it has also been used in humans for the treatment of urogenital and gastrointestinal spasms.[2]
Mechanism of action
Denaverine, like papaverine, acts as a phosphodiesterase inhibitor. Additionally, it has anticholinergic effects.[3]
References
- ^ Committee for Veterinary Medicinal Products: Denavering Hydrochloride Summary Report
- ^ Dootz H, Kuhlmann A, Hoffmann K, eds. (2005). Rote Liste (in German) (2005 ed.). Aulendorf: Editio Cantor. 77 023. ISBN 3-87193-306-6.
- ^ Dinnendahl V, Fricke U, eds. (2010). Arzneistoff-Profile (in German). Vol. 4 (23 ed.). Eschborn, Germany: Govi Pharmazeutischer Verlag. ISBN 978-3-7741-9846-3.
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