Difetarsone
Chemical compound
- P01AR02 (WHO) QP51AD02 (WHO)
- [4-[2-[(4-arsonophenyl)amino]ethylamino]phenyl] arsonic acid
- 3639-19-8
- 68199
- 61506
- G4G9J3Q65W
- D07357
- DTXSID30189913
Difetarsone is an antiprotozoal agent. Various studies have shown it to be particularly effective against Trichuris trichiura, commonly known as the whipworm. Prior to the drugs use in the early 1970s, there were few effective treatments for this infection.[1] It has also been used to treat Entamoeba histolytica infections.[2]
Difetarsone often has minor side effects, which include rashes, nausea and vomiting. It has also resulted in angioedema in at least one known case.[2]
References
- ^ Leary PM, Jones C, Douglas F, Boyd ST (June 1974). "Difetarsone in outpatient treatment of Trichuris trichiura infestation". Archives of Disease in Childhood. 49 (6): 486–8. doi:10.1136/adc.49.6.486. PMC 1648795. PMID 4851370.
- ^ a b Aronson JK (2009). Meyler's Side Effects of Antimicrobial Drugs. p. 834. ISBN 9780080932934. Retrieved October 7, 2013.
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Antiparasitics – antiprotozoal agents – agents against amoebozoa/amebicide (P01)
| Tissue amebicides |
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| Luminal amebicides |
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| Other/ungrouped |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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