Dimethylcarbamoyl fluoride
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Preferred IUPAC name Dimethylcarbamoyl fluoride | |
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Properties | |
Chemical formula | C3H6FNO |
Molar mass | 91.085 g·mol−1 |
Appearance | Colorless liquid |
Solubility in water | Soluble |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards | Highly toxic |
Related compounds | |
Related compounds | Dimethylcarbamoyl chloride |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Dimethylcarbamoyl fluoride is a chemical compound that can be produced by fluorination of dimethylcarbamoyl chloride with potassium fluoride.[1] It's a colorless liquid that is soluble and stable in water.[2][3]
Dimethylcarbamoyl fluoride is highly toxic because it's a potent cholinesterase inhibitor and is lethal even at low doses.[2][3]
See also
- Dimethylcarbamoyl chloride
References
- ^ Cuomo, John; Olofson, R. A. (March 1979). "Efficient and convenient synthesis of fluoroformates and carbamoyl fluorides". The Journal of Organic Chemistry. 44 (6): 1016–1017. doi:10.1021/jo01320a034.
- ^ a b Augustinsson, K.B.; Casida, J.E. (December 1959). "Enzymic hydrolysis of N:N-dimethylcarbamoyl fluoride". Biochemical Pharmacology. 3 (1): 60–67. doi:10.1016/0006-2952(59)90009-7. PMID 13795122.
- ^ a b MYERS, DK (April 1956). "Studies on cholinesterase. 10. Return of cholinesterase activity in the rat after inhibition by carbamoyl fluorides". The Biochemical Journal. 62 (4): 556–63. doi:10.1042/bj0620556. PMC 1215962. PMID 13315214.
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Acetylcholine metabolism and transport modulators
(modulators)
(modulators)
CHTTooltip Choline transporter |
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VAChTTooltip Vesicular acetylcholine transporter |
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(modulators)
Inhibitors |
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Enhancers |
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- See also
- Receptor/signaling modulators
- Muscarinic acetylcholine receptor modulators
- Nicotinic acetylcholine receptor modulators
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