GZMB |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1FQ3, 1IAU |
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Identifiers |
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Aliases | GZMB, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT, granzyme B, C11 |
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External IDs | OMIM: 123910; MGI: 109267; HomoloGene: 108184; GeneCards: GZMB; OMA:GZMB - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 14 (human)[1] |
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| Band | 14q12 | Start | 24,630,954 bp[1] |
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End | 24,634,267 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 14 (mouse)[2] |
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| Band | 14 C3|14 28.19 cM | Start | 56,496,295 bp[2] |
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End | 56,499,717 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - granulocyte
- blood
- mononuclear cell
- monocyte
- spleen
- bone marrow
- decidua
- lymph node
- right lung
- appendix
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| Top expressed in | - gastrula
- jejunum
- duodenum
- decidua
- blood
- intestinal villus
- embryo
- pharynx
- uterus
- seminal vesicula
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - peptidase activity
- protein binding
- serine-type peptidase activity
- serine-type endopeptidase activity
- hydrolase activity
| Cellular component | - cytosol
- membrane
- immunological synapse
- nucleus
- mitochondrion
- secretory granule
- cytoplasm
| Biological process | - cytolysis
- proteolysis
- positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
- natural killer cell mediated cytotoxicity
- apoptotic process
- granzyme-mediated apoptotic signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 14: 24.63 – 24.63 Mb | Chr 14: 56.5 – 56.5 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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