Gallate decarboxylase

gallate decarboxylase
Identifiers
EC no.4.1.1.59
CAS no.37290-51-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins

The enzyme gallate decarboxylase (EC 4.1.1.59) catalyzes the chemical reaction

3,4,5-trihydroxybenzoate {\displaystyle \rightleftharpoons } pyrogallol + CO2

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3,4,5-trihydroxybenzoate carboxy-lyase (pyrogallol-forming). Other names in common use include gallic acid decarboxylase and gallate carboxy-lyase. This enzyme participates in benzoate degradation via CoA ligation.

References

  • Grant DJ, Patel JC (1969). "The non-oxidative decarboxylation of p-hydroxybenzoic acid, gentisic acid, protocatechuic acid and gallic acid by Klebsiella aerogenes (Aerobacter aerogenes)". Antonie van Leeuwenhoek. 35 (3): 325–43. doi:10.1007/BF02219153. PMID 5309907.
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Carbon–carbon lyases (EC 4.1)
4.1.1: Carboxy-lyases4.1.2: Aldehyde-lyases4.1.3: Oxo-acid-lyases4.1.99: Other
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