Girinimbine
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Preferred IUPAC name 3,3,5-Trimethyl-3,11-dihydropyrano[3,2-a]carbazole | |
Other names Girinimbin | |
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Properties | |
Chemical formula | C18H17NO |
Molar mass | 263.340 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Girinimbine is a carbazole alkaloid isolated from the curry tree (Murraya koenigii) along with the related alkaloids mahanimbine,[1] koenimbine,[2] isomahanine, mahanine, and others.
A 2011 study of girinimbine found that it inhibited the growth and induced apoptosis in human hepatocellular carcinoma, Hep G2 cells in vitro.[3]
References
- ^ CID 167963 from PubChem
- ^ Metabocard for Koenimbine
- ^ Syam, Suvitha; Abdul, Ahmad Bustamam; Sukari, Mohd. Aspollah; Mohan, Syam; Abdelwahab, Siddig Ibrahim; Wah, Tang Sook (2011). "The Growth Suppressing Effects of Girinimbine on Hepg2 Involve Induction of Apoptosis and Cell Cycle Arrest". Molecules. 16 (8): 7155–70. doi:10.3390/molecules16087155. PMC 6264672. PMID 21862957.
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