BAG6 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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1WX9, 4DWF, 4EEW, 4WWR, 4X86, 2N9P |
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Identifiers |
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Aliases | BAG6, BAG-6, BAT3, D6S52E, G3, HLA-B associated transcript 3, BCL2 associated athanogene 6, BAG cochaperone 6 |
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External IDs | OMIM: 142590; MGI: 1919439; HomoloGene: 3409; GeneCards: BAG6; OMA:BAG6 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 6 (human)[1] |
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| Band | 6p21.33 | Start | 31,639,028 bp[1] |
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End | 31,652,705 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 17 (mouse)[2] |
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| Band | 17 B1|17 18.59 cM | Start | 35,135,178 bp[2] |
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End | 35,147,322 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right testis
- left testis
- right lobe of thyroid gland
- right uterine tube
- apex of heart
- pituitary gland
- ganglionic eminence
- left lobe of thyroid gland
- anterior pituitary
- muscle of thigh
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| Top expressed in | - seminiferous tubule
- spermatid
- spermatocyte
- neural layer of retina
- ventricular zone
- muscle of thigh
- superior frontal gyrus
- dentate gyrus of hippocampal formation granule cell
- yolk sac
- lip
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - ribosome binding
- misfolded protein binding
- Hsp70 protein binding
- polyubiquitin modification-dependent protein binding
- proteasome binding
- protein binding
- ubiquitin-specific protease binding
- ubiquitin protein ligase binding
- signaling receptor binding
- identical protein binding
| Cellular component | - cytoplasm
- cytosol
- membrane
- intracellular membrane-bounded organelle
- nucleoplasm
- BAT3 complex
- nucleus
- extracellular region
- extracellular exosome
| Biological process | - regulation of apoptotic process
- negative regulation of proteolysis
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
- cell differentiation
- ubiquitin-dependent protein catabolic process
- kidney development
- embryo development
- lung development
- immune system process
- positive regulation of ERAD pathway
- protein stabilization
- negative regulation of apoptotic process
- internal peptidyl-lysine acetylation
- brain development
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
- regulation of cell population proliferation
- synaptonemal complex assembly
- spermatogenesis
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process
- protein localization to cytosolic proteasome complex involved in ERAD pathway
- maintenance of unfolded protein involved in ERAD pathway
- tail-anchored membrane protein insertion into ER membrane
- ER-associated misfolded protein catabolic process
- immune response-activating cell surface receptor signaling pathway
- apoptotic process
- natural killer cell activation
- proteasomal protein catabolic process
- ubiquitin-dependent ERAD pathway
- endoplasmic reticulum stress-induced pre-emptive quality control
- transport
- chromatin organization
- proteasome-mediated ubiquitin-dependent protein catabolic process
- regulation of embryonic development
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | ENSG00000204463 ENSG00000228760 ENSG00000234651 ENSG00000229524 ENSG00000096155
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ENSG00000227761 ENSG00000233348 |
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UniProt | | |
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RefSeq (mRNA) | NM_001098534 NM_001199697 NM_001199698 NM_004639 NM_080702
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NM_080703 |
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NM_001252468 NM_001252469 NM_057171 |
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RefSeq (protein) | |
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NP_001092004 NP_001186626 NP_001186627 NP_542433 NP_542434 |
| NP_001239397 NP_001239398 NP_476512 NP_001359189 NP_001359190
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NP_001359191 NP_001359194 NP_001359195 NP_001359196 NP_001359197 NP_001359198 NP_001359199 NP_001359200 NP_001359201 NP_001359202 NP_001359203 NP_001359204 NP_001359205 NP_001359206 NP_001359207 NP_001359208 NP_001359209 NP_001359210 NP_001359211 NP_001359212 NP_001359213 NP_001359214 NP_001359215 NP_001359216 NP_001359217 NP_001359218 NP_001359219 NP_001359220 NP_001391257 NP_001391258 NP_001391259 NP_001391260 NP_001391256 |
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Location (UCSC) | Chr 6: 31.64 – 31.65 Mb | Chr 17: 35.14 – 35.15 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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