HMGXB3

Protein-coding gene in the species Homo sapiens
HMGXB3
Identifiers
AliasesHMGXB3, HMGX3, SMF, HMG-box containing 3
External IDsMGI: 2441817; HomoloGene: 44229; GeneCards: HMGXB3; OMA:HMGXB3 - orthologs
Gene location (Human)
Chromosome 5 (human)
Chr.Chromosome 5 (human)[1]
Chromosome 5 (human)
Genomic location for HMGXB3
Genomic location for HMGXB3
Band5q32Start150,000,046 bp[1]
End150,053,142 bp[1]
Gene location (Mouse)
Chromosome 18 (mouse)
Chr.Chromosome 18 (mouse)[2]
Chromosome 18 (mouse)
Genomic location for HMGXB3
Genomic location for HMGXB3
Band18|18 E1Start61,264,349 bp[2]
End61,310,122 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • olfactory bulb

  • stromal cell of endometrium

  • right uterine tube

  • vena cava

  • parotid gland

  • cardia

  • nasal epithelium

  • lateral nuclear group of thalamus

  • pylorus

  • trachea
Top expressed in
  • Rostral migratory stream

  • spermatocyte

  • zygote

  • spermatid

  • tail of embryo

  • secondary oocyte

  • substantia nigra

  • retinal pigment epithelium

  • female urethra

  • motor neuron
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • DNA binding
  • kinase activity
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • nucleus
  • cellular component
Biological process
  • phosphorylation
  • biological process
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

22993

106894

Ensembl

ENSG00000113716

ENSMUSG00000024622

UniProt

Q12766
Q562E5

n/a

RefSeq (mRNA)

NM_014983
NM_001366501

NM_134134
NM_178277

RefSeq (protein)

NP_055798
NP_001353430
NP_055798.2

n/a

Location (UCSC)Chr 5: 150 – 150.05 MbChr 18: 61.26 – 61.31 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

HMG-box containing 3 is a protein that in humans is encoded by the HMGXB3 gene. [5]

Function

This gene is one of the non-canonical high mobility group (HMG) genes. The encoded protein contains an HMG-box domain found in DNA binding proteins such as transcription factors and chromosomal proteins.

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000113716 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024622 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: HMG-box containing 3". Retrieved 2016-03-29.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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