Itruvone
Experimental drug
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Other names | PH10; PH10A; PH10 NS; Pregn-4-en-20-yn-3-one |
Routes of administration | Intranasal (spray) |
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Formula | C21H28O |
Molar mass | 296.454 g·mol−1 |
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Itruvone (INNTooltip International Nonproprietary Name; developmental code name PH10), also known as pregn-4-en-20-yn-3-one, is a vomeropherine which is under development by VistaGen Therapeutics as a nasal spray for the treatment of major depressive disorder.[1][2][3][4][5][6]
See also
References
- ^ "PH-10 Nasal Spray". AdisInsight. Springer Nature Switzerland AG.
- ^ Monti L, Liebowitz MR (February 2022). "Neural circuits of anxiolytic and antidepressant pherine molecules". CNS Spectr. 27 (1): 66–72. doi:10.1017/S109285292000190X. PMID 33092667. S2CID 225053518.
- ^ "VistaGen Therapeutics Acquires Worldwide Rights to Develop and Commercialize PH10, a First-in-Class Intranasally Administered Neuroactive Steroid with Rapid-onset Antidepressant Effects for Major Depressive Disorder Demonstrated in Phase 2a Study :: VistaGen Therapeutics, Inc. (VTGN)". VistaGen Therapeutics, Inc. Retrieved 2019-12-19.
- ^ "Health Care Digest: A small biotech goes head first, Gilead's lower tax rate and more". www.bizjournals.com. San Francisco Business Times. October 29, 2018. Retrieved 20 July 2020.
- ^ Liebowitz MR, Nicolini H, Monti L, Hanover R (2013). PH 10 may be a new rapidly acting intranasally administered antidepressant. Vol. American Society of Clinical Psychopharmacology (ASCP) Annual Meeting, Miami, FL.
- ^ Jancin B (2013). "Novel intranasal antidepressant shows results after 1 week". Clinical Psychiatry News. Retrieved 13 January 2016.
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Human pheromones and vomeropherines
Steroids | |
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Volatile amines |
- ETA
- Fasedienol (PH94B; Aloradine)
- Itruvone (PH10)
- PDD
- PH15
- PH30
- PH56
- PH78
- PH80
- PH84
- Salubrin
- See also: Steroid hormones
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