KANSL3

Protein-coding gene in the species Homo sapiens
KANSL3
Identifiers
AliasesKANSL3, KIAA1310, NSL3, Rcd1, FLJ10081, KAT8 regulatory NSL complex subunit 3
External IDsOMIM: 617742; MGI: 1918055; HomoloGene: 9949; GeneCards: KANSL3; OMA:KANSL3 - orthologs
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for KANSL3
Genomic location for KANSL3
Band2q11.2Start96,593,170 bp[1]
End96,642,787 bp[1]
Gene location (Mouse)
Chromosome 1 (mouse)
Chr.Chromosome 1 (mouse)[2]
Chromosome 1 (mouse)
Genomic location for KANSL3
Genomic location for KANSL3
Band1|1 BStart36,374,811 bp[2]
End36,408,262 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sperm

  • tibia

  • renal medulla

  • cardia

  • urethra

  • parietal pleura

  • tendon of biceps brachii

  • visceral pleura

  • pylorus

  • middle temporal gyrus
Top expressed in
  • spermatocyte

  • Rostral migratory stream

  • otolith organ

  • utricle

  • neural layer of retina

  • molar

  • spermatid

  • hand

  • habenula

  • seminiferous tubule
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • histone acetyltransferase activity (H4-K5 specific)
  • histone acetyltransferase activity (H4-K16 specific)
  • histone acetyltransferase activity (H4-K8 specific)
Cellular component
  • histone acetyltransferase complex
  • nucleolus
  • intracellular membrane-bounded organelle
  • nucleus
  • nucleoplasm
  • NSL complex
Biological process
  • histone H4-K16 acetylation
  • histone H4-K8 acetylation
  • histone H4-K5 acetylation
  • chromatin organization
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55683

226976

Ensembl

ENSG00000114982

ENSMUSG00000010453

UniProt

Q9P2N6

A2RSY1

RefSeq (mRNA)
NM_001115016
NM_017991
NM_001349256
NM_001349257
NM_001349258

NM_001349259
NM_001349260
NM_001349261
NM_001349262

NM_172652
NM_001310513

RefSeq (protein)
NP_001108488
NP_001336185
NP_001336186
NP_001336187
NP_001336188

NP_001336189
NP_001336190
NP_001336191

NP_001297442
NP_766240

Location (UCSC)Chr 2: 96.59 – 96.64 MbChr 1: 36.37 – 36.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

KANSL3, or KAT8 regulatory NSL complex subunit 3 is a protein that in humans is encoded by the KANSL3 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000114982 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000010453 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: FLJ10081 hypothetical protein FLJ10081".

Further reading

  • Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
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