KDM4D |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/2/28/Protein_KDM4D_PDB_3DXT.png/250px-Protein_KDM4D_PDB_3DXT.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3DXT, 3DXU, 4D6Q, 4D6R, 4D6S, 4HON, 4HOO, 5FP9, 5F5A, 5FP8, 5FPA, 5FPB, 5FP4, 5F5C |
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Identifiers |
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Aliases | KDM4D, JMJD2D, lysine demethylase 4D |
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External IDs | OMIM: 609766; MGI: 3606484; HomoloGene: 69244; GeneCards: KDM4D; OMA:KDM4D - orthologs |
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Gene location (Human) |
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![Chromosome 11 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/4/4e/Ideogram_human_chromosome_11.svg/300px-Ideogram_human_chromosome_11.svg.png) | Chr. | Chromosome 11 (human)[1] |
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| Band | 11q21 | Start | 94,973,709 bp[1] |
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End | 94,999,519 bp[1] |
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Gene location (Mouse) |
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![Chromosome 9 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/4/41/Ideogram_house_mouse_chromosome_9.svg/260px-Ideogram_house_mouse_chromosome_9.svg.png) | Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9|9 A1- A2 | Start | 14,373,844 bp[2] |
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End | 14,411,778 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - buccal mucosa cell
- left testis
- right testis
- testicle
- gonad
- sperm
- secondary oocyte
- ventricular zone
- islet of Langerhans
- stromal cell of endometrium
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| Top expressed in | - spermatocyte
- seminiferous tubule
- spermatid
- lumbar spinal ganglion
- embryo
- lumbar subsegment of spinal cord
- facial motor nucleus
- primary visual cortex
- superior frontal gyrus
- neural layer of retina
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/a/af/PBB_GE_JMJD2D_220278_at_fs.png/250px-PBB_GE_JMJD2D_220278_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - oxidoreductase activity
- dioxygenase activity
- metal ion binding
- histone demethylase activity
- histone H3-methyl-lysine-9 demethylase activity
- DNA-binding transcription repressor activity, RNA polymerase II-specific
- chromatin binding
- damaged DNA binding
- chromatin DNA binding
- methylated histone binding
| Cellular component | - blood microparticle
- nucleus
- nucleoplasm
- site of double-strand break
- pericentric heterochromatin
- histone methyltransferase complex
| Biological process | - regulation of protein phosphorylation
- cellular response to ionizing radiation
- regulation of transcription, DNA-templated
- positive regulation of chromatin binding
- double-strand break repair via homologous recombination
- transcription, DNA-templated
- positive regulation of double-strand break repair via nonhomologous end joining
- histone H3-K9 demethylation
- negative regulation of transcription by RNA polymerase II
- chromatin organization
- cellular response to DNA damage stimulus
- negative regulation of histone H3-K9 trimethylation
- chromatin remodeling
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 11: 94.97 – 95 Mb | Chr 9: 14.37 – 14.41 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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