MIS18BP1

Protein-coding gene in the species Homo sapiens
MIS18BP1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

1WGX

Identifiers
AliasesMIS18BP1, C14orf106, HSA242977, KNL2, M18BP1, MIS18 binding protein 1
External IDsOMIM: 618139; MGI: 2145099; HomoloGene: 10147; GeneCards: MIS18BP1; OMA:MIS18BP1 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for MIS18BP1
Genomic location for MIS18BP1
Band14q21.2Start45,203,190 bp[1]
End45,253,540 bp[1]
Gene location (Mouse)
Chromosome 12 (mouse)
Chr.Chromosome 12 (mouse)[2]
Chromosome 12 (mouse)
Genomic location for MIS18BP1
Genomic location for MIS18BP1
Band12|12 C1Start65,179,508 bp[2]
End65,219,378 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • monocyte

  • ventricular zone

  • testicle

  • epithelium of colon

  • tendon of biceps brachii

  • gonad

  • ganglionic eminence

  • buccal mucosa cell

  • Achilles tendon

  • rectum
Top expressed in
  • genital tubercle

  • tail of embryo

  • abdominal wall

  • zygote

  • medial ganglionic eminence

  • primitive streak

  • maxillary prominence

  • renal corpuscle

  • oocyte

  • mandibular prominence
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • DNA binding
  • protein binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • chromosome
  • chromosome, centromeric region
  • nucleus
  • nucleoplasm
Biological process
  • cell division
  • cell cycle
  • CENP-A containing chromatin assembly
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55320

217653

Ensembl

ENSG00000129534

ENSMUSG00000047534

UniProt

Q6P0N0

Q80WQ8

RefSeq (mRNA)

NM_018353

NM_172578

RefSeq (protein)

NP_060823

NP_766166

Location (UCSC)Chr 14: 45.2 – 45.25 MbChr 12: 65.18 – 65.22 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

MIS18 binding protein 1 is a protein that in humans is encoded by the MIS18BP1 gene.[5][6][7] The gene is also known as LKNL2, M18BP1, C14orf106, and HSA242977.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000129534 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047534 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "MIS18 binding protein 1". Retrieved 2011-12-04.
  6. ^ Maddox PS, Hyndman F, Monen J, Oegema K, Desai A (Mar 2007). "Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin". J Cell Biol. 176 (6): 757–63. doi:10.1083/jcb.200701065. PMC 2064049. PMID 17339379.
  7. ^ Fujita Y, Hayashi T, Kiyomitsu T, Toyoda Y, Kokubu A, Obuse C, Yanagida M (Jan 2007). "Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1". Dev Cell. 12 (1): 17–30. doi:10.1016/j.devcel.2006.11.002. PMID 17199038.

Further reading

  • Fujita Y, Hayashi T, Kiyomitsu T, Toyoda Y, Kokubu A, Obuse C, Yanagida M (January 2007). "Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1". Dev. Cell. 12 (1): 17–30. doi:10.1016/j.devcel.2006.11.002. PMID 17199038.
  • Maddox PS, Hyndman F, Monen J, Oegema K, Desai A (March 2007). "Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin". J. Cell Biol. 176 (6): 757–63. doi:10.1083/jcb.200701065. PMC 2064049. PMID 17339379.
  • Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (April 2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.


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