NPRL2 |
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Identifiers |
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Aliases | NPRL2, NPR2, NPR2L, TUSC4, NPR2-like, GATOR1 complex subunit, FFEVF2, NPR2 like, GATOR1 complex subunit |
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External IDs | OMIM: 607072; MGI: 1914482; HomoloGene: 4771; GeneCards: NPRL2; OMA:NPRL2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 3 (human)[1] |
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| Band | 3p21.31 | Start | 50,347,330 bp[1] |
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End | 50,350,826 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 9 (mouse)[2] |
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| Band | 9|9 F1 | Start | 107,419,425 bp[2] |
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End | 107,422,905 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - granulocyte
- right hemisphere of cerebellum
- body of pancreas
- Skeletal muscle tissue of rectus abdominis
- muscle of thigh
- pituitary gland
- anterior pituitary
- prefrontal cortex
- right frontal lobe
- apex of heart
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| Top expressed in | - interventricular septum
- primary oocyte
- right kidney
- proximal tubule
- spermatocyte
- neural tube
- superior frontal gyrus
- dentate gyrus of hippocampal formation granule cell
- secondary oocyte
- nucleus of stria terminalis
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - protein kinase activity
- protein binding
- GTPase activator activity
| Cellular component | - GATOR1 complex
- lysosome
- lysosomal membrane
- membrane
| Biological process | - negative regulation of TOR signaling
- cellular response to amino acid starvation
- negative regulation of kinase activity
- positive regulation of GTPase activity
- protein phosphorylation
- cellular response to nitrogen starvation
- positive regulation of autophagy
- regulation of autophagosome assembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 3: 50.35 – 50.35 Mb | Chr 9: 107.42 – 107.42 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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