NPTN |
---|
|
Identifiers |
---|
Aliases | NPTN, GP55, GP65, SDFR1, SDR1, np55, np65, neuroplastin |
---|
External IDs | OMIM: 612820; MGI: 108077; HomoloGene: 7531; GeneCards: NPTN; OMA:NPTN - orthologs |
---|
Gene location (Human) |
---|
| Chr. | Chromosome 15 (human)[1] |
---|
| Band | 15q24.1 | Start | 73,560,014 bp[1] |
---|
End | 73,634,134 bp[1] |
---|
|
Gene location (Mouse) |
---|
| Chr. | Chromosome 9 (mouse)[2] |
---|
| Band | 9|9 B | Start | 58,582,240 bp[2] |
---|
End | 58,657,955 bp[2] |
---|
|
RNA expression pattern |
---|
Bgee | Human | Mouse (ortholog) |
---|
Top expressed in | - Brodmann area 23
- lateral nuclear group of thalamus
- cerebellar vermis
- germinal epithelium
- jejunal mucosa
- tail of epididymis
- bronchial epithelial cell
- visceral pleura
- orbitofrontal cortex
- caput epididymis
|
| Top expressed in | - nucleus accumbens
- superior frontal gyrus
- cerebellar cortex
- olfactory tubercle
- lobe of cerebellum
- primary visual cortex
- cerebellar vermis
- cingulate gyrus
- lateral geniculate nucleus
- prefrontal cortex
|
| More reference expression data |
|
---|
BioGPS | | More reference expression data |
|
---|
|
Gene ontology |
---|
Molecular function | - transmembrane transporter binding
- fibroblast growth factor receptor binding
- cell adhesion molecule binding
- type 1 fibroblast growth factor receptor binding
- cell-cell adhesion mediator activity
- protein binding
| Cellular component | - integral component of membrane
- synaptic membrane
- membrane
- postsynaptic density
- plasma membrane
- inhibitory synapse
- dendrite
- presynaptic membrane
- cell surface
- axon
- Schaffer collateral - CA1 synapse
- glutamatergic synapse
- GABA-ergic synapse
- integral component of presynaptic active zone membrane
- integral component of postsynaptic density membrane
- immunological synapse
| Biological process | - visual learning
- positive regulation of long-term synaptic potentiation
- nervous system development
- cell adhesion
- positive regulation of protein localization
- positive regulation of ERK1 and ERK2 cascade
- positive regulation of long-term neuronal synaptic plasticity
- positive regulation of neuron projection development
- positive regulation of cytosolic calcium ion concentration
- homophilic cell adhesion via plasma membrane adhesion molecules
- modulation of chemical synaptic transmission
- synapse organization
- regulation of receptor localization to synapse
- excitatory synapse assembly
- positive regulation of protein phosphorylation
- positive regulation of fibroblast growth factor receptor signaling pathway
- long-term potentiation
- axon guidance
- dendrite self-avoidance
- trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission
- negative regulation of cytokine production
- cellular calcium ion homeostasis
| Sources:Amigo / QuickGO |
|
Orthologs |
---|
Species | Human | Mouse |
---|
Entrez | | |
---|
Ensembl | | |
---|
UniProt | | |
---|
RefSeq (mRNA) | |
---|
NM_001161363 NM_001161364 NM_012428 NM_017455 |
| |
---|
NM_001293673 NM_009145 NM_001357751 |
|
---|
RefSeq (protein) | |
---|
NP_001154835 NP_001154836 NP_036560 NP_059429 |
| |
---|
NP_001280602 NP_033171 NP_001344680 NP_001392991 |
|
---|
Location (UCSC) | Chr 15: 73.56 – 73.63 Mb | Chr 9: 58.58 – 58.66 Mb |
---|
PubMed search | [3] | [4] |
---|
|
Wikidata |
View/Edit Human | View/Edit Mouse |
|