Niguldipine
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IUPAC name 3-3-(4,4-Diphenyl-1-piperidyl)propyl 5-methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | |
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Properties | |
Chemical formula | C36H39N3O6 |
Molar mass | 609.71136 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Niguldipine is a calcium channel blocker and α1-adrenergic receptor antagonist.[1]
References
- ^ Boer R, Grassegger A, Schudt C, Glossmann H (May 1989). "(+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors". European Journal of Pharmacology. 172 (2): 131–45. doi:10.1016/0922-4106(89)90004-7. PMID 2548881.
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(antagonize α-adrenergic
vasoconstriction)
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Peripheral |
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Serotonin receptor antagonists | |
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Endothelin receptor antagonists (for PHTooltip Pulmonary hypertension) |
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- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it. |
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