Nucleoside transporter

Transport protein that transports nucleosides across cell membranes
Part of a series on
Purinergic signalling
Simplified illustration of extracellular purinergic signalling
Concepts

Purinergic signalling

  • Receptors
  • Pannexins
  • Ectonucleotidases
  • Metabolism
Membrane transporters

Nucleoside transporters

  • Concentrative
  • Equilibrative
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Nucleoside transporters (NTs) are a group of membrane transport proteins which transport nucleoside substrates like adenosine across the membranes of cells and/or vesicles.[1] There are two known types of nucleoside transporters, concentrative nucleoside transporters (CNTs; SLC28) and equilibrative nucleoside transporters (ENTs; SLC29), as well as possibly a yet-unidentified vesicular transporter.[1]

References

  1. ^ a b Molina-Arcas M, Casado FJ, Pastor-Anglada M (October 2009). "Nucleoside transporter proteins". Current Vascular Pharmacology. 7 (4): 426–34. PMID 19485885. Archived from the original on 2013-01-13.

Further reading

  • Molina-Arcas M, Casado FJ, Pastor-Anglada M (October 2009). "Nucleoside Transporter Proteins". Current Vascular Pharmacology. 7 (4): 426–34. PMID 19485885. Archived from the original on 2013-01-13.
  • Molina-Arcas M, Trigueros-Motos L, Casado FJ, Pastor-Anglada M (June 2008). "Physiological and pharmacological roles of nucleoside transporter proteins". Nucleosides, Nucleotides & Nucleic Acids. 27 (6): 769–78. doi:10.1080/15257770802145819. PMID 18600539.
  • Gray JH, Owen RP, Giacomini KM (February 2004). "The concentrative nucleoside transporter family, SLC28". Pflügers Archiv: European Journal of Physiology. 447 (5): 728–34. doi:10.1007/s00424-003-1107-y. PMID 12856181.
  • Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (February 2004). "The equilibrative nucleoside transporter family, SLC29". Pflügers Archiv: European Journal of Physiology. 447 (5): 735–43. doi:10.1007/s00424-003-1103-2. PMID 12838422.
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Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
By group
SLC1–10
(1):
  • high affinity glutamate and neutral amino-acid transporter
(2):
(3):
(4):
(5):
(6):
(7):
(8):
  • Na+/Ca2+ exchanger
(9):
(10):
SLC11–20
(11):
(12):
(13):
(14):
(15):
(16):
(17):
(18):
(19):
(20):
SLC21–30
(21):
(22):
(23):
  • Na+-dependent ascorbic acid transporter
(24):
  • Na+/(Ca2+-K+) exchanger
(25):
(26):
(27):
(28):
(29):
(30):
SLC31–40
(31):
(32):
(33):
(34):
(35):
(36):
(37):
(38):
(39):
(40):
  • basolateral iron transporter
SLC41–48
(41):
(42):
(43):
  • Na+-independent, system-L like amino-acid transporter
(44):
(45):
(46):
(47):
(48):
SLCO1–4
Symporter, Cotransporter
  • Na+/K+,Cl−
  • Na+/Pi3
  • Na+/Cl−
  • Na+/glucose
  • Na+/I−
  • Cl−/K+
Antiporter (exchanger)
  • Na+/H+
  • Na+/Ca2+
    • Na+/(Ca2+-K+) - Cl−/HCO−
      3       (Band 3)
  • Cl−-formate
  • Cl−-oxalate
see also solute carrier disorders
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Receptor
(ligands)
P0 (adenine)
P1
(adenosine)
P2
(nucleotide)
P2X
(ATPTooltip Adenosine triphosphate)
P2Y
Transporter
(blockers)
CNTsTooltip Concentrative nucleoside transporters
ENTsTooltip Equilibrative nucleoside transporters
PMATTooltip Plasma membrane monoamine transporter
Enzyme
(inhibitors)
XOTooltip Xanthine oxidase
Others
Others
See also: Receptor/signaling modulators


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