OR13J1

Protein-coding gene in the species Homo sapiens
OR13J1
Identifiers
AliasesOR13J1, OR9-2, olfactory receptor family 13 subfamily J member 1
External IDsMGI: 1860080; HomoloGene: 10460; GeneCards: OR13J1; OMA:OR13J1 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for OR13J1
Genomic location for OR13J1
Band9p13.3Start35,869,463 bp[1]
End35,870,401 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for OR13J1
Genomic location for OR13J1
Band4|4 A5Start43,704,562 bp[2]
End43,710,255 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • prefrontal cortex

  • primary visual cortex

  • anterior cingulate cortex

  • hippocampus proper

  • right frontal lobe

  • superior frontal gyrus

  • putamen

  • dorsolateral prefrontal cortex

  • temporal lobe

  • amygdala
Top expressed in
  • intestinal villus

  • Ileal epithelium

  • perirhinal cortex

  • entorhinal cortex

  • choroid plexus of fourth ventricle

  • CA3 field

  • lactiferous gland

  • extraocular muscle

  • medial ganglionic eminence

  • tracheobronchial tree
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • signal transduction
  • response to stimulus
  • detection of chemical stimulus involved in sensory perception of smell
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

392309

56015

Ensembl

ENSG00000168828

ENSMUSG00000046450

UniProt

Q8NGT2

Q9QZ18

RefSeq (mRNA)

NM_001004487

NM_019486

RefSeq (protein)

NP_001004487

NP_062359

Location (UCSC)Chr 9: 35.87 – 35.87 MbChr 4: 43.7 – 43.71 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 13J1 is a protein that in humans is encoded by the OR13J1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168828 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046450 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR13J1 olfactory receptor, family 13, subfamily J, member 1".

Further reading

  • Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.
  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
  • Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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