PDZD11

Protein-coding gene in the species Homo sapiens

PDZD11

Available structures

PDB

Ortholog search: PDBe RCSB

List of PDB id codes
1WI2

Identifiers

Aliases

PDZD11, AIPP1, PDZK11, PISP, PDZ domain containing 11

External IDs

OMIM: 300632; MGI: 1919871; HomoloGene: 9530; GeneCards: PDZD11; OMA:PDZD11 - orthologs

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	Xq13.1	Start	70,286,595 bp^[1]
Band	Xq13.1	End	70,290,514 bp^[1]

Gene location (Mouse)

Chr.	X chromosome (mouse)^[2]

Band	X\|X C3	Start	99,666,489 bp^[2]
Band	X\|X C3	End	99,670,174 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

mucosa of ileum

myocardium of left ventricle

parotid gland

lateral nuclear group of thalamus

hypothalamus

prefrontal cortex

cardiac muscle tissue of right atrium

nasal epithelium

substantia nigra

amygdala

Top expressed in

right kidney

ventricular zone

yolk sac

morula

choroid plexus of fourth ventricle

medial ganglionic eminence

blastocyst

embryo

seminal vesicula

embryo

More reference expression data

BioGPS

n/a

Gene ontology
Molecular function	protein C-terminus binding protein binding
Cellular component	cytoplasm extracellular region cytosol synapse cell-cell junction presynapse basolateral plasma membrane
Biological process	maintenance of epithelial cell apical/basal polarity protein localization to basolateral plasma membrane neurotransmitter secretion biotin metabolic process pantothenate metabolic process antimicrobial humoral response ion transmembrane transport transmembrane transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


51248


72621

Ensembl


ENSG00000120509


ENSMUSG00000015668

UniProt


Q5EBL8


Q9CZG9

RefSeq (mRNA)


NM_016484


NM_028303 NM_001356384

RefSeq (protein)

NP_057568 NP_001357103 NP_001357104 NP_001357105 NP_001357106
NP_001357107


NP_082579 NP_001343313

Location (UCSC)

Chr X: 70.29 – 70.29 Mb

Chr X: 99.67 – 99.67 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

PDZ domain-containing protein 11 is a protein that in humans is encoded by the PDZD11 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120509 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015668 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (Nov 2000). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
^ Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, Chen J, Chow B, Chui C, Crowley C, Currell B, Deuel B, Dowd P, Eaton D, Foster J, Grimaldi C, Gu Q, Hass PE, Heldens S, Huang A, Kim HS, Klimowski L, Jin Y, Johnson S, Lee J, Lewis L, Liao D, Mark M, Robbie E, Sanchez C, Schoenfeld J, Seshagiri S, Simmons L, Singh J, Smith V, Stinson J, Vagts A, Vandlen R, Watanabe C, Wieand D, Woods K, Xie MH, Yansura D, Yi S, Yu G, Yuan J, Zhang M, Zhang Z, Goddard A, Wood WI, Godowski P, Gray A (Oct 2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
^ "Entrez Gene: PDZD11 PDZ domain containing 11".

Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Goellner GM, DeMarco SJ, Strehler EE (2003). "Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants". Ann. N. Y. Acad. Sci. 986 (1): 461–71. Bibcode:2003NYASA.986..461G. doi:10.1111/j.1749-6632.2003.tb07230.x. PMID 12763866. S2CID 447365.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
Stephenson SE, Dubach D, Lim CM, et al. (2005). "A single PDZ domain protein interacts with the Menkes copper ATPase, ATP7A. A new protein implicated in copper homeostasis". J. Biol. Chem. 280 (39): 33270–9. doi:10.1074/jbc.M505889200. hdl:10536/DRO/DU:30039503. PMID 16051599.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.