PLXNB2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | PLXNB2, MM1, Nbla00445, PLEXB2, dJ402G11.3, plexin B2 |
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External IDs | OMIM: 604293; MGI: 2154239; HomoloGene: 66630; GeneCards: PLXNB2; OMA:PLXNB2 - orthologs |
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Gene location (Human) |
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![Chromosome 22 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/6/62/Ideogram_human_chromosome_22.svg/300px-Ideogram_human_chromosome_22.svg.png) | Chr. | Chromosome 22 (human)[1] |
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| Band | 22q13.33 | Start | 50,274,979 bp[1] |
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End | 50,307,646 bp[1] |
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Gene location (Mouse) |
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![Chromosome 15 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/1/13/Ideogram_house_mouse_chromosome_15.svg/260px-Ideogram_house_mouse_chromosome_15.svg.png) | Chr. | Chromosome 15 (mouse)[2] |
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| Band | 15 E3|15 44.68 cM | Start | 89,039,752 bp[2] |
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End | 89,064,991 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right uterine tube
- right hemisphere of cerebellum
- right lobe of thyroid gland
- left lobe of thyroid gland
- anterior pituitary
- stromal cell of endometrium
- nasal epithelium
- body of stomach
- olfactory zone of nasal mucosa
- decidua
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| Top expressed in | - pyloric antrum
- choroid plexus of fourth ventricle
- calvaria
- corneal stroma
- genital tubercle
- epithelium of stomach
- stroma of bone marrow
- ventricular zone
- conjunctival fornix
- Rostral migratory stream
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/3/37/PBB_GE_PLXNB2_208890_s_at_fs.png/250px-PBB_GE_PLXNB2_208890_s_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- semaphorin receptor activity
| Cellular component | - integral component of membrane
- membrane
- plasma membrane
- cell surface
- extracellular exosome
- integral component of plasma membrane
- semaphorin receptor complex
| Biological process | - regulation of protein phosphorylation
- negative regulation of cell adhesion
- regulation of GTPase activity
- positive regulation of axonogenesis
- multicellular organism development
- neural tube closure
- brain development
- regulation of cell shape
- neuroblast proliferation
- regulation of neuron migration
- semaphorin-plexin signaling pathway
- signal transduction
- positive regulation of neuron projection development
- homophilic cell adhesion via plasma membrane adhesion molecules
- regulation of cell migration
- semaphorin-plexin signaling pathway involved in axon guidance
- excitatory synapse assembly
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001159521 NM_001284506 NM_138749 |
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RefSeq (protein) | NP_036533 NP_001363793 NP_001363794 NP_001363795 NP_001363796
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NP_001363797 NP_001363798 NP_001363799 NP_001363800 NP_001363801 NP_001363802 NP_001363803 NP_001363804 NP_001363805 NP_001363806 NP_001363807 NP_001363808 NP_001363809 NP_001363810 NP_001363811 NP_001363812 NP_001363813 NP_001363814 NP_001363815 |
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NP_001152993 NP_001271435 NP_620088 |
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Location (UCSC) | Chr 22: 50.27 – 50.31 Mb | Chr 15: 89.04 – 89.06 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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