PMVK |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | PMVK, HUMPMKI, PMK, PMKA, PMKASE, POROK1, phosphomevalonate kinase |
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External IDs | OMIM: 607622; MGI: 1915853; HomoloGene: 4779; GeneCards: PMVK; OMA:PMVK - orthologs |
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EC number | 2.7.4.2 |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1q21.3 | Start | 154,924,740 bp[1] |
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End | 154,936,719 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 F1 | Start | 89,361,848 bp[2] |
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End | 89,376,320 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - apex of heart
- right lobe of liver
- anterior pituitary
- nucleus accumbens
- C1 segment
- skin of abdomen
- anterior cingulate cortex
- skin of leg
- right adrenal cortex
- right auricle
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| Top expressed in | - fossa
- lip
- condyle
- motor neuron
- facial motor nucleus
- trigeminal ganglion
- ectoderm
- otic placode
- supraoptic nucleus
- otic vesicle
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - transferase activity
- nucleotide binding
- ATP binding
- kinase activity
- phosphomevalonate kinase activity
| Cellular component | - cytoplasm
- cytosol
- peroxisome
- extracellular exosome
- membrane
| Biological process | - cholesterol biosynthetic process
- steroid metabolic process
- isopentenyl diphosphate biosynthetic process, mevalonate pathway
- response to cholesterol
- cholesterol metabolic process
- sterol biosynthetic process
- isoprenoid biosynthetic process
- phosphorylation
- lipid metabolism
- steroid biosynthetic process
- regulation of cholesterol biosynthetic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_006556 NM_001323011 NM_001323012 NM_001348696 |
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NM_026784 NM_027348 NM_001310640 |
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RefSeq (protein) | |
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NP_001309940 NP_001309941 NP_006547 NP_001335625 |
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NP_001297569 NP_081060 NP_081624 |
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Location (UCSC) | Chr 1: 154.92 – 154.94 Mb | Chr 3: 89.36 – 89.38 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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