Psychosine
Names | |
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IUPAC name (2S,3R,4E)-2-Amino-3-hydroxyoctadec-4-en-1-yl β-D-galactopyranoside | |
Systematic IUPAC name (2R,3R,4S,5R,6R)-2-{[(2S,3R,4E)-2-Amino-3-hydroxyoctadec-4-en-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol | |
Identifiers | |
CAS Number |
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3D model (JSmol) |
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Beilstein Reference | 52571 |
ChEBI |
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ChemSpider |
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ECHA InfoCard | 100.164.357 |
EC Number |
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KEGG |
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PubChem CID |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C24H47NO7 |
Molar mass | 461.640 g·mol−1 |
Hazards | |
GHS labelling: | |
Pictograms | |
Warning | |
Hazard statements | H302, H312, H332 |
Precautionary statements | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P501 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Psychosine is a highly cytotoxic lipid that accumulates in the nervous system in the absence of galactosylceramidase.[1]
Chemically, it is a galactoside of sphingosine.
References
- ^ Hawkins-Salsbury, J. A.; Parameswar, A. R.; Jiang, X; Schlesinger, P. H.; Bongarzone, E; Ory, D. S.; Demchenko, A. V.; Sands, M. S. (2013). "Psychosine, the cytotoxic sphingolipid that accumulates in globoid cell leukodystrophy, alters membrane architecture". The Journal of Lipid Research. 54 (12): 3303–3311. doi:10.1194/jlr.M039610. PMC 3826678. PMID 24006512.
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