RC3H1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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3X1O, 4QIK, 4QIL, 4ULW, 4YWQ |
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Identifiers |
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Aliases | RC3H1, RNF198, ROQUIN, ring finger and CCCH-type domains 1, FHL6, IMDSHY |
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External IDs | OMIM: 609424; MGI: 2685397; HomoloGene: 19036; GeneCards: RC3H1; OMA:RC3H1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1q25.1 | Start | 173,931,084 bp[1] |
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End | 174,022,357 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 H2.1 | Start | 160,733,988 bp[2] |
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End | 160,802,548 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - tibialis anterior muscle
- skin of thigh
- mucosa of ileum
- deltoid muscle
- buccal mucosa cell
- skin of hip
- skin of arm
- pancreatic epithelial cell
- cardiac muscle tissue of right atrium
- trabecular bone
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| Top expressed in | - hand
- aortic valve
- ascending aorta
- otolith organ
- utricle
- fossa
- condyle
- facial motor nucleus
- Paneth cell
- conjunctival fornix
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - ubiquitin protein ligase activity
- metal ion binding
- mRNA binding
- RNA stem-loop binding
- mRNA 3'-UTR binding
- RNA binding
- double-stranded RNA binding
- ubiquitin-protein transferase activity
- protein binding
- zinc ion binding
- transferase activity
- miRNA binding
| Cellular component | - cytoplasm
- P-body
- cytoplasmic stress granule
| Biological process | - regulation of T cell proliferation
- regulation of T cell activation
- B cell homeostasis
- spleen development
- positive regulation of NIK/NF-kappaB signaling
- T cell homeostasis
- T cell proliferation
- regulation of gene expression
- lymph node development
- T follicular helper cell differentiation
- negative regulation of T-helper cell differentiation
- regulation of mRNA stability
- positive regulation of mRNA catabolic process
- regulation of germinal center formation
- posttranscriptional regulation of gene expression
- negative regulation of germinal center formation
- negative regulation of B cell proliferation
- cellular response to interleukin-1
- protein ubiquitination
- nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
- P-body assembly
- regulation of T cell receptor signaling pathway
- nuclear-transcribed mRNA catabolic process
- negative regulation of activated T cell proliferation
- 3'-UTR-mediated mRNA destabilization
- protein polyubiquitination
- T cell receptor signaling pathway
- negative regulation of T-helper 17 cell differentiation
- regulation of miRNA metabolic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001300850 NM_001300851 NM_001300852 NM_172071 |
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RefSeq (protein) | |
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NP_001287779 NP_001287780 NP_001287781 NP_742068 NP_001287779.1 |
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Location (UCSC) | Chr 1: 173.93 – 174.02 Mb | Chr 1: 160.73 – 160.8 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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