Ro-318220
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Preferred IUPAC name 3-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-1H-indol-1-yl}propyl carbamimidothioate | |
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Properties | |
Chemical formula | C25H23N5O2S |
Molar mass | 457.55 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references |
Chemical compound
Ro-318220 is a protein kinase C (PKC) inhibitor of the bisindolylmaleimide class.[1]
References
- ^ Beltman, Jerlyn; Frank McCormick; Simon J. Cook (1996). "The Selective Protein Kinase C Inhibitor, Ro-31-8220, Inhibits Mitogen-activated Protein Kinase Phosphatase-1 (MKP-1) Expression, Induces c-Jun Expression, and Activates Jun N-terminal Kinase". Journal of Biological Chemistry. 271: 27018–27024. doi:10.1074/jbc.271.43.27018.