SLA2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | SLA2, C20orf156, MARS, SLAP-2, SLAP2, Src-like-adaptor 2, Src like adaptor 2 |
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External IDs | OMIM: 606577; MGI: 1925049; HomoloGene: 49989; GeneCards: SLA2; OMA:SLA2 - orthologs |
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Gene location (Human) |
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![Chromosome 20 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Ideogram_human_chromosome_20.svg/300px-Ideogram_human_chromosome_20.svg.png) | Chr. | Chromosome 20 (human)[1] |
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| Band | 20q11.23 | Start | 36,612,318 bp[1] |
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End | 36,646,196 bp[1] |
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Gene location (Mouse) |
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![Chromosome 2 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Ideogram_house_mouse_chromosome_2.svg/260px-Ideogram_house_mouse_chromosome_2.svg.png) | Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2|2 H1 | Start | 156,714,377 bp[2] |
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End | 156,729,112 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - buccal mucosa cell
- granulocyte
- monocyte
- blood
- testicle
- lymph node
- spleen
- appendix
- oocyte
- bone marrow cells
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| Top expressed in | - thymus
- zygote
- primary oocyte
- secondary oocyte
- granulocyte
- embryo
- blood
- embryo
- pharynx
- morula
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - protein binding
- protein N-terminus binding
- non-membrane spanning protein tyrosine kinase activity
- signaling receptor binding
- 1-phosphatidylinositol-3-kinase regulator activity
| Cellular component | - cytoplasm
- late endosome
- plasma membrane
- endosome membrane
- membrane
- cytoplasmic vesicle
- nucleoplasm
- Golgi apparatus
- intracellular membrane-bounded organelle
- extrinsic component of cytoplasmic side of plasma membrane
- phosphatidylinositol 3-kinase complex
| Biological process | - negative regulation of calcium-mediated signaling
- negative regulation of B cell activation
- intracellular receptor signaling pathway
- negative regulation of transcription by RNA polymerase II
- T cell activation
- B cell mediated immunity
- regulation of immune response
- antigen receptor-mediated signaling pathway
- positive regulation of signal transduction
- transmembrane receptor protein tyrosine kinase signaling pathway
- cell migration
- cell differentiation
- peptidyl-tyrosine autophosphorylation
- regulation of cell population proliferation
- innate immune response
- regulation of signal transduction
- regulation of phosphatidylinositol 3-kinase activity
- negative regulation of insulin receptor signaling pathway
- phosphatidylinositol phosphate biosynthetic process
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 20: 36.61 – 36.65 Mb | Chr 2: 156.71 – 156.73 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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