SLAMF8 |
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Identifiers |
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Aliases | SLAMF8, BLAME, CD353, SBBI42, SLAM family member 8 |
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External IDs | OMIM: 606620; MGI: 1921998; HomoloGene: 10589; GeneCards: SLAMF8; OMA:SLAMF8 - orthologs |
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Gene location (Human) |
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![Chromosome 1 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/Ideogram_human_chromosome_1.svg/300px-Ideogram_human_chromosome_1.svg.png) | Chr. | Chromosome 1 (human)[1] |
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| Band | 1q23.2 | Start | 159,826,811 bp[1] |
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End | 159,837,492 bp[1] |
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Gene location (Mouse) |
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![Chromosome 1 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/f/fb/Ideogram_house_mouse_chromosome_1.svg/260px-Ideogram_house_mouse_chromosome_1.svg.png) | Chr. | Chromosome 1 (mouse)[2] |
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| Band | 1|1 H3 | Start | 172,409,325 bp[2] |
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End | 172,418,135 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - appendix
- lymph node
- testicle
- lower lobe of lung
- decidua
- spleen
- superficial temporal artery
- amniotic fluid
- gallbladder
- rectum
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| Top expressed in | - mesenteric lymph nodes
- embryo
- spleen
- lumbar subsegment of spinal cord
- morula
- granulocyte
- right kidney
- blastocyst
- thymus
- subcutaneous adipose tissue
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/0/0f/PBB_GE_SLAMF8_219386_s_at_fs.png/250px-PBB_GE_SLAMF8_219386_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/d/df/PBB_GE_SLAMF8_219385_at_fs.png/250px-PBB_GE_SLAMF8_219385_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - signaling receptor activity
- identical protein binding
| Cellular component | - membrane
- integral component of membrane
- cell surface
| Biological process | - leukocyte chemotaxis involved in inflammatory response
- B-1 B cell lineage commitment
- negative regulation of macrophage chemotaxis
- regulation of NAD(P)H oxidase activity
- defense response to bacterium
- regulation of kinase activity
- regulation of B cell differentiation
- negative regulation of respiratory burst involved in inflammatory response
- negative regulation of monocyte chemotaxis
- phagosome acidification
- negative regulation of neutrophil migration
- negative regulation of dendritic cell chemotaxis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 159.83 – 159.84 Mb | Chr 1: 172.41 – 172.42 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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