SMYD4

Protein-coding gene in the species Homo sapiens
SMYD4
Identifiers
AliasesSMYD4, ZMYND21, SET and MYND domain containing 4
External IDsMGI: 2442796; HomoloGene: 35098; GeneCards: SMYD4; OMA:SMYD4 - orthologs
Gene location (Human)
Chromosome 17 (human)
Chr.Chromosome 17 (human)[1]
Chromosome 17 (human)
Genomic location for SMYD4
Genomic location for SMYD4
Band17p13.3Start1,779,485 bp[1]
End1,830,634 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for SMYD4
Genomic location for SMYD4
Band11|11 B5Start75,239,259 bp[2]
End75,296,531 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gastrocnemius muscle

  • muscle of thigh

  • deltoid muscle

  • endothelial cell

  • gonad

  • popliteal artery

  • tibial arteries

  • Achilles tendon

  • gastric mucosa

  • left ovary
Top expressed in
  • extraocular muscle

  • substantia nigra

  • vestibular membrane of cochlear duct

  • Epithelium of choroid plexus

  • lumbar spinal ganglion

  • right kidney

  • endothelial cell of lymphatic vessel

  • medullary collecting duct

  • neural tube

  • ventricular zone
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

114826

319822

Ensembl

ENSG00000186532

ENSMUSG00000018809

UniProt

Q8IYR2

Q8BTK5

RefSeq (mRNA)

NM_052928

NM_001102611
NM_177009

RefSeq (protein)

NP_443160

NP_001096081

Location (UCSC)Chr 17: 1.78 – 1.83 MbChr 11: 75.24 – 75.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

SET and MYND domain-containing protein 4 is a protein that in humans is encoded by the SMYD4 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186532 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018809 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Nagase T; Kikuno R; Ohara O (Sep 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Res. 8 (4): 179–87. doi:10.1093/dnares/8.4.179. PMID 11572484.
  6. ^ "Entrez Gene: SMYD4 SET and MYND domain containing 4".

Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Xu XR, Huang J, Xu ZG, et al. (2002). "Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver". Proc. Natl. Acad. Sci. U.S.A. 98 (26): 15089–94. Bibcode:2001PNAS...9815089X. doi:10.1073/pnas.241522398. PMC 64988. PMID 11752456.
  • Bonaldo MF; Lennon G; Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.


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