SRPK2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | SRPK2, SFRSK2, SRSF protein kinase 2 |
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External IDs | OMIM: 602980; MGI: 1201408; HomoloGene: 101663; GeneCards: SRPK2; OMA:SRPK2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 7 (human)[1] |
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| Band | 7q22.3 | Start | 105,110,704 bp[1] |
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End | 105,399,308 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5 A3|5 10.36 cM | Start | 23,503,264 bp[2] |
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End | 23,684,617 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sperm
- pons
- secondary oocyte
- middle temporal gyrus
- lateral nuclear group of thalamus
- entorhinal cortex
- parietal lobe
- postcentral gyrus
- left testis
- right testis
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| Top expressed in | - Rostral migratory stream
- medial dorsal nucleus
- medial geniculate nucleus
- ventral tegmental area
- spermatid
- lateral geniculate nucleus
- seminiferous tubule
- pontine nuclei
- medial vestibular nucleus
- globus pallidus
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- nucleotide binding
- protein kinase activity
- 14-3-3 protein binding
- kinase activity
- protein serine/threonine kinase activity
- protein binding
- ATP binding
- magnesium ion binding
- RNA binding
| Cellular component | - cytoplasm
- nucleoplasm
- nucleolus
- nucleus
- cytosol
| Biological process | - cell differentiation
- intracellular signal transduction
- nuclear speck organization
- phosphorylation
- mRNA processing
- regulation of mRNA splicing, via spliceosome
- protein phosphorylation
- spliceosomal complex assembly
- positive regulation of neuron apoptotic process
- negative regulation of viral genome replication
- positive regulation of gene expression
- positive regulation of cell cycle
- angiogenesis
- RNA splicing
- positive regulation of cell population proliferation
- positive regulation of viral genome replication
- innate immune response
- regulation of gene expression
- regulation of mRNA processing
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001278273 NM_182691 NM_182692 NM_001350738 NM_001350739
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NM_001350740 NM_001350741 NM_001350742 NM_001350743 NM_001350744 NM_001350745 NM_001350746 |
| NM_009274 NM_001359172 NM_001359173 NM_001359174 NM_001359175
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NM_001359176 |
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RefSeq (protein) | NP_001265202 NP_872633 NP_872634 NP_001337667 NP_001337668
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NP_001337669 NP_001337670 NP_001337671 NP_001337672 NP_001337673 NP_001337674 NP_001337675 |
| NP_033300 NP_001346101 NP_001346102 NP_001346103 NP_001346104
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NP_001346105 NP_001394425 NP_001394427 NP_001394428 NP_001394429 NP_001394430 NP_001394431 NP_001394432 NP_001394433 NP_001394434 NP_001394435 NP_001394436 NP_001394437 NP_001394438 NP_001394439 NP_001394440 NP_001394441 NP_001394442 NP_001394443 NP_001394444 NP_001394445 NP_001394446 NP_001394447 NP_001394448 NP_001394449 NP_001394450 NP_001394451 NP_001394452 |
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Location (UCSC) | Chr 7: 105.11 – 105.4 Mb | Chr 5: 23.5 – 23.68 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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