SUV39H2 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | SUV39H2, KMT1B, suppressor of variegation 3-9 homolog 2, SUV39H2 histone lysine methyltransferase |
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External IDs | OMIM: 606503; MGI: 1890396; HomoloGene: 32548; GeneCards: SUV39H2; OMA:SUV39H2 - orthologs |
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Gene location (Human) |
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![Chromosome 10 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/300px-Ideogram_human_chromosome_10.svg.png) | Chr. | Chromosome 10 (human)[1] |
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| Band | 10p13 | Start | 14,878,820 bp[1] |
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End | 14,904,315 bp[1] |
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Gene location (Mouse) |
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![Chromosome 2 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/b/bb/Ideogram_house_mouse_chromosome_2.svg/260px-Ideogram_house_mouse_chromosome_2.svg.png) | Chr. | Chromosome 2 (mouse)[2] |
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| Band | 2 A1|2 1.95 cM | Start | 3,456,852 bp[2] |
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End | 3,476,068 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - sperm
- secondary oocyte
- left testis
- right testis
- ventricular zone
- ganglionic eminence
- gonad
- testicle
- stromal cell of endometrium
- islet of Langerhans
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| Top expressed in | - tail of embryo
- secondary oocyte
- genital tubercle
- zygote
- spermatid
- primary oocyte
- ventricular zone
- epiblast
- primitive streak
- embryo
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/e/e2/PBB_GE_SUV39H2_219262_at_fs.png/250px-PBB_GE_SUV39H2_219262_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - methyltransferase activity
- transferase activity
- histone methyltransferase activity (H3-K9 specific)
- transcription cis-regulatory region binding
- metal ion binding
- protein binding
- histone-lysine N-methyltransferase activity
- zinc ion binding
- S-adenosyl-L-methionine binding
| Cellular component | - chromosome
- nucleoplasm
- chromatin
- chromosome, centromeric region
- nucleus
| Biological process | - chromatin remodeling
- cell differentiation
- regulation of transcription, DNA-templated
- rhythmic process
- histone H3-K9 dimethylation
- negative regulation of circadian rhythm
- negative regulation of transcription by RNA polymerase II
- transcription, DNA-templated
- histone H3-K9 trimethylation
- methylation
- histone lysine methylation
- cell cycle
- negative regulation of transcription, DNA-templated
- cellular response to hypoxia
- chromatin organization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001193424 NM_001193425 NM_001193426 NM_001193427 NM_024670 |
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RefSeq (protein) | |
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NP_001180353 NP_001180354 NP_001180355 NP_001180356 NP_078946 |
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Location (UCSC) | Chr 10: 14.88 – 14.9 Mb | Chr 2: 3.46 – 3.48 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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