Stephen Crohn
American man immune to HIV/AIDS due to a genetic mutation
Stephen Crohn | |
---|---|
Born | Stephen Lyon Crohn (1946-09-05)September 5, 1946 New York City, U.S. |
Died | August 23, 2013(2013-08-23) (aged 66) New York City, U.S. |
Occupation | Artist |
Stephen Lyon Crohn (September 5, 1946 – August 23, 2013),[1] also known as "the man who can't catch AIDS", was a man notable for a genetic mutation that caused him to be immune to AIDS. He was a great-nephew of Burrill Bernard Crohn, for whom Crohn's disease is named.[2]
Crohn had the Δ32 mutation on the CCR5 receptor,[3][4] a protein on the surface of white blood cells that is involved in the immune system and serves as an access route for many forms of HIV to enter and infect host cells. This mutation rendered him effectively immune to many forms of HIV.
Death
Crohn committed suicide by a drug overdose on oxycodone and benzodiazepines at the age of 66.[5][6]
See also
- Timothy Ray Brown
- Adam Castillejo
- Innate resistance to HIV
- Long-term nonprogressor
- HIV/AIDS research
References
- ^ John Schwartz (September 14, 2013). "Stephen Crohn, Who Furthered AIDS Study, Dies at 66". The New York Times. Retrieved September 16, 2013.
- ^ "In memoriam: Steve Crohn". Hudson Valley One. 20 September 2013. Retrieved 30 September 2020.
- ^ Tom Wilkie (September 16, 2013). "The man who can't catch AIDS". The Independent. Archived from the original on 2022-05-25. Retrieved September 16, 2013.
- ^ NOVA (PBS airdate: February 2, 1999) (February 2, 1999). "Surviving AIDS". NOVA (PBS). Retrieved September 16, 2013.
{{cite web}}
: CS1 maint: numeric names: authors list (link) - ^ News Limited Network (September 16, 2013). "The man who couldn't catch AIDS, Stephen Crohn, dies from suicide aged 66". Australia: Herald Sun. Retrieved September 16, 2013.
- ^ Jesse Green (2014-06-13). "The Man Who Was Immune to AIDS". NYMag.com. Retrieved 2015-01-20.
External links
- Video and text from a PBS documentary about Stephen Crohn and the discovery of CCR5
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