Syrette : Wikipedia, the free encyclopedia

Syrette

Liquid injection device

British syrette containing Omnopon, c. 1990s

Syrette of morphine from World War II, on display at the Army Medical Services Museum

A syrette is a single-use device for injecting liquid through a needle. It is similar to a syringe except that it has a sealed squeeze tube instead of a rigid tube and piston. It was developed by the pharmaceutical manufacturer E.R. Squibb & Sons (eventually merged into the current day Bristol-Myers Squibb) just prior to World War II (WWII).^[1]

Instructions for using the syrette from the FM 21-11 Basic Field Manual – First Aid for Soldiers, April 7, 1943

Diagram showing wire loop pin

In WWII, the morphine syrette was included in first aid kits. It had a wire loop with a guard at the end of a hollow needle that was used to break a seal where the needle was attached to the tube. The wire loop was then removed and the needle was inserted under the skin at a shallow angle and the tube slowly squeezed from the sealed end (see subcutaneous injection).^[2] After injection the used tube was often pinned to the receiving soldier's collar to inform others of the dose administered.^[1]

The syrette was adopted for use by the United States Army in 1940.^[1] The US military also distributed atropine in syrettes.^{[citation needed]} Chemical treatment was subsequently distributed in autoinjector form.^{[citation needed]}

References

^ ^a ^b ^c "The painkiller of battlefields". Beaches of Normandy Tours. Retrieved Aug 17, 2024.{{cite web}}: CS1 maint: url-status (link)
^ "War Department FM 21-11 Basic Field Manual – First Aid for Soldiers" (PDF). All Americans. April 7, 1943. Retrieved Aug 17, 2024.{{cite web}}: CS1 maint: url-status (link)

External links

Museum of Drugs Morphine

Routes of administration, dosage forms

Oral

Digestive tract (enteral)

Solids	Tablet Capsule Pastille Time release technology Osmotic delivery system
Liquids	Decoction Elixir Electuary Emulsion Effervescent powder or tablet Herbal tea Hydrogel Molecular encapsulation Powder Softgel Solution Suspension Syrup Tincture

Oral mucosa (buccal, sublabial, sublingual)

Solids	Orally disintegrating tablet Film Lollipop Sublingual drops Lozenges Effervescent tablet Chewing gum
Liquids	Mouthwash Toothpaste Ointment Spray

Respiratory tract (inhalation)

Solids	Dry-powder inhaler Smoking	0 0
Liquids	Anesthetic vaporizer Heated humidified high-flow therapy Medical inhalants Metered-dose inhaler (MDI) Nebulizer Vaporizer
Gas	Oxygen mask and Nasal cannula Oxygen concentrator Anaesthetic machine Medical inhalants Relative analgesia machine

Ophthalmic,
otic, nasal

Intrauterine device (IUD)

Extra-amniotic infusion

Intravesical infusion

Rectal (enteral)

Paste

DMSO solution

Transfersome vesicles

Cream

(into tissue/blood)

Skin (transdermal)	Intradermal Subcutaneous Injector pen Transdermal implant
Organs	Intracavernous Intravitreal Intra-articular
Central nervous system	Intracerebral Intrathecal Epidural
Circulatory, musculoskeletal	Intravenous Intracardiac Intramuscular Intraosseous Intraperitoneal Nanocell injection Patient-controlled analgesia pump PIC line