TSEN2 |
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Identifiers |
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Aliases | TSEN2, PCH2B, SEN2, SEN2L, tRNA splicing endonuclease subunit 2 |
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External IDs | OMIM: 608753; MGI: 2141599; HomoloGene: 41622; GeneCards: TSEN2; OMA:TSEN2 - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3p25.2 | Start | 12,484,421 bp[1] |
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End | 12,541,549 bp[1] |
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Gene location (Mouse) |
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![Chromosome 6 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_6.svg/260px-Ideogram_house_mouse_chromosome_6.svg.png) | Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6|6 E3 | Start | 115,521,625 bp[2] |
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End | 115,555,589 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - buccal mucosa cell
- mucosa of transverse colon
- gonad
- ventricular zone
- testicle
- gastrocnemius muscle
- body of pancreas
- cerebellar hemisphere
- right uterine tube
- muscle of thigh
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| Top expressed in | - Rostral migratory stream
- yolk sac
- epiblast
- primitive streak
- interventricular septum
- hand
- superior cervical ganglion
- otolith organ
- embryo
- utricle
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/0/0b/PBB_GE_TSEN2_219581_at_fs.png/250px-PBB_GE_TSEN2_219581_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - tRNA-intron endonuclease activity
- protein binding
- lyase activity
- nucleic acid binding
- nuclease activity
| Cellular component | - centrosome
- nucleolus
- nucleus
- tRNA-intron endonuclease complex
- nucleoplasm
- cytosol
| Biological process | - mRNA processing
- tRNA-type intron splice site recognition and cleavage
- RNA phosphodiester bond hydrolysis, endonucleolytic
- tRNA splicing, via endonucleolytic cleavage and ligation
- RNA phosphodiester bond hydrolysis
- tRNA processing
- nucleic acid phosphodiester bond hydrolysis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001145392 NM_001145393 NM_001145394 NM_001145395 NM_025265
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NM_001321277 NM_001321278 NM_001321279 |
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RefSeq (protein) | NP_001138864 NP_001138865 NP_001138866 NP_001308206 NP_001308207
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NP_001308208 NP_079541 |
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Location (UCSC) | Chr 3: 12.48 – 12.54 Mb | Chr 6: 115.52 – 115.56 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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