Toxoflavin
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Names | |
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IUPAC name 1,6-Dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione | |
Other names Toxoflavine; Xanthothricin; Xanthotricin | |
Identifiers | |
CAS Number |
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3D model (JSmol) |
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ChEBI |
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ChEMBL |
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ChemSpider |
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ECHA InfoCard | 100.213.079 ![]() |
PubChem CID |
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UNII |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C7H7N5O2 |
Molar mass | 193.166 g·mol−1 |
Appearance | Bright yellow solid |
Melting point | 172 to 173 °C (342 to 343 °F; 445 to 446 K) (decomposes) |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) | 1.7 mg/kg (IV, mouse) 8.4 mg/kg (oral, mouse) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ![]() ![]() ![]() Infobox references |
Chemical compound
Toxoflavin is a toxin produced by a variety of bacteria including Burkholderia gladioli. It also has antibiotic properties.[3]
Toxoflavin acts as a pH indicator, changing between yellow and colorless at pH 10.5.[1]
References
- ^ a b Merck Index, 11th Edition, 9480
- ^ Toxoflavin, at the Comparative Toxicogenomics Database
- ^ Machlowitz, Roy A.; Fisher, W. P.; McKay, Betsey S.; Tytell, Alfred A.; Charney, Jesse (1954). "Xanthothricin, a new antibiotic". Antibiotics & Chemotherapy (Northfield, Ill.). Antibiotics and Chemotherapy. 4 (3): 259–261. PMID 24542943.
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