Tramazoline
Chemical used as a nasal decongestant
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- R01AA09 (WHO)
- N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
- 1082-57-1
N
- 5524
- 5323
N
- SLE31693IV
- D08624
N
- ChEMBL32573
N
- DTXSID5046936
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Tramazoline is a chemical that is used in the form of tramazoline hydrochloride in nasal decongestant preparations.[1] It is an α-adrenergic receptor agonist that inhibits secretion of nasal mucus.
It was patented in 1961 and came into medical use in 1962.[2]
Brand names
- Australia
- Spray-Tish[3]
- Rhinaspray
- Austria
- Rhinorix
- Belgium
- Rhinospray
- Bulgaria
- Muconasal Plus
- Czech Republic
- Muconasal Plus
- Germany
- Biciron
- Ellatun
- Rhinospray
- Hungary
- Rhinospray Plus
- Italy
- Rinogutt
- Fexallegra nasale (Tramazoline + Chlorpheniramine, 1 mg/mL + 3.55 mg/mL)
- The Netherlands
- Bisolnasal
- Portugal
- Rhinospray
- Romania
- Muconasal Plus (older)
- Muconasal (newer)
- Russia
- Adrianol (tramazoline + phenylephrine)
- Lasolvan Rhino
- Spain
- Rhinospray
- Slovakia
- Muconasal Plus
- Ukraine
- Lasorin
References
- ^ "Spray-Tish Consumer Information". MyDr.com.au. Retrieved 16 April 2011.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 552. ISBN 978-3-527-60749-5.
- ^ "Consumer medicine information: Spray-Tish". nps.org.au. NPS MedicineWise. 8 September 2017. Retrieved September 13, 2021.
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Decongestants and other nasal preparations (R01)
Sympathomimetics, plain | |
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Antiallergic agents, excluding corticosteroids | |
Corticosteroids | |
Other nasal preparations | |
Combination products |
Sympathomimetics
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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