Tumor necrosis factor receptor 1

Function

Clinical significance

Interactions

• BAG4,^[15][16]
• CASP10,^[17][18]
• FADD,^[17][19]
• IKK2,^[20][21]
• JAK1,^[22][23]
• JAK2,^[22]
• PIP4K2B,^[24]
• PSMD2,^[25][26]
• RIPK1,^{[27][28][29][30][31][32]}
• SUMO1,^[33][34]
• TRADD^{[15][19][27][30][35][36][37]}
• TRAF2,^[19][27][35]
• TRPC4AP,^[38]
• TNF,^[39][40] and
• UBE2I.^[41]

See also

References

1. ^ ^{a b c} GRCh38: Ensembl release 89: ENSG00000067182 – Ensembl, May 2017
2. ^ ^{a b c} GRCm38: Ensembl release 89: ENSMUSG00000030341 – Ensembl, May 2017
3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. ^ Baker E, Chen LZ, Smith CA, Callen DF, Goodwin R, Sutherland GR (November 1991). "Chromosomal location of the human tumor necrosis factor receptor genes". Cytogenetics and Cell Genetics. 57 (2–3): 117–118. doi:10.1159/000133127. PMID 1655358.
6. ^ Schall TJ, Lewis M, Koller KJ, Lee A, Rice GC, Wong GH, et al. (April 1990). "Molecular cloning and expression of a receptor for human tumor necrosis factor". Cell. 61 (2): 361–370. doi:10.1016/0092-8674(90)90816-W. PMID 2158863. S2CID 36187863.
7. ^ Offermanns S, Rosenthal W (2008). Encyclopedia of Molecular Pharmacology. Vol. 1 (2nd ed.). Heidelberg, Germany: Springer. p. 1248. ISBN 9783540389163.
8. ^ "Entrez Gene: TNFRSF1A tumor necrosis factor receptor superfamily, member 1A".
9. ^ Kümpfel T, Hohlfeld R (October 2009). "Multiple sclerosis. TNFRSF1A, TRAPS and multiple sclerosis". Nature Reviews. Neurology. 5 (10): 528–529. doi:10.1038/nrneurol.2009.154. PMID 19794511. S2CID 40665495.
10. ^ International Multiple Sclerosis Genetics Consortium (April 2011). "The genetic association of variants in CD6, TNFRSF1A and IRF8 to multiple sclerosis: a multicenter case-control study". PLOS ONE. 6 (4): e18813. Bibcode:2011PLoSO...618813.. doi:10.1371/journal.pone.0018813. PMC 3084233. PMID 21552549.
11. ^ Hope S, Melle I, Aukrust P, Steen NE, Birkenaes AB, Lorentzen S, et al. (November 2009). "Similar immune profile in bipolar disorder and schizophrenia: selective increase in soluble tumor necrosis factor receptor I and von Willebrand factor". Bipolar Disorders. 11 (7): 726–734. doi:10.1111/j.1399-5618.2009.00757.x. hdl:10852/34620. PMID 19839997.
12. ^ Hope S, Ueland T, Steen NE, Dieset I, Lorentzen S, Berg AO, et al. (April 2013). "Interleukin 1 receptor antagonist and soluble tumor necrosis factor receptor 1 are associated with general severity and psychotic symptoms in schizophrenia and bipolar disorder". Schizophrenia Research. 145 (1–3): 36–42. doi:10.1016/j.schres.2012.12.023. PMID 23403415.
13. ^ Buchhave P, Zetterberg H, Blennow K, Minthon L, Janciauskiene S, Hansson O (November 2010). "Soluble TNF receptors are associated with Aβ metabolism and conversion to dementia in subjects with mild cognitive impairment". Neurobiology of Aging. 31 (11): 1877–1884. doi:10.1016/j.neurobiolaging.2008.10.012. PMID 19070941. S2CID 34595960.
14. ^ Diniz BS, Teixeira AL, Ojopi EB, Talib LL, Mendonça VA, Gattaz WF, et al. (2010). "Higher serum sTNFR1 level predicts conversion from mild cognitive impairment to Alzheimer's disease". Journal of Alzheimer's Disease. 22 (4): 1305–1311. doi:10.3233/JAD-2010-100921. PMID 20930310.
15. ^ ^{a b} Jiang Y, Woronicz JD, Liu W, Goeddel DV (January 1999). "Prevention of constitutive TNF receptor 1 signaling by silencer of death domains". Science. 283 (5401): 543–546. Bibcode:1999Sci...283..543J. doi:10.1126/science.283.5401.543. PMID 9915703.
16. ^ Miki K, Eddy EM (April 2002). "Tumor necrosis factor receptor 1 is an ATPase regulated by silencer of death domain". Molecular and Cellular Biology. 22 (8): 2536–2543. doi:10.1128/MCB.22.8.2536-2543.2002. PMC 133739. PMID 11909948.
17. ^ ^{a b} Gajate C, Mollinedo F (March 2005). "Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy". The Journal of Biological Chemistry. 280 (12): 11641–11647. doi:10.1074/jbc.M411781200. PMID 15659383.
18. ^ Vincenz C, Dixit VM (March 1997). "Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling". The Journal of Biological Chemistry. 272 (10): 6578–6583. doi:10.1074/jbc.272.10.6578. PMID 9045686.
19. ^ ^{a b c} Hsu H, Shu HB, Pan MG, Goeddel DV (January 1996). "TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways". Cell. 84 (2): 299–308. doi:10.1016/S0092-8674(00)80984-8. PMID 8565075. S2CID 13171355.
20. ^ Zhang SQ, Kovalenko A, Cantarella G, Wallach D (March 2000). "Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation". Immunity. 12 (3): 301–311. doi:10.1016/S1074-7613(00)80183-1. PMID 10755617.
21. ^ Chaudhary PM, Eby MT, Jasmin A, Kumar A, Liu L, Hood L (September 2000). "Activation of the NF-kappaB pathway by caspase 8 and its homologs". Oncogene. 19 (39): 4451–4460. doi:10.1038/sj.onc.1203812. PMID 11002417.
22. ^ ^{a b} Guo D, Dunbar JD, Yang CH, Pfeffer LM, Donner DB (March 1998). "Induction of Jak/STAT signaling by activation of the type 1 TNF receptor". Journal of Immunology. 160 (6): 2742–2750. doi:10.4049/jimmunol.160.6.2742. PMID 9510175.
23. ^ Miscia S, Marchisio M, Grilli A, Di Valerio V, Centurione L, Sabatino G, et al. (January 2002). "Tumor necrosis factor alpha (TNF-alpha) activates Jak1/Stat3-Stat5B signaling through TNFR-1 in human B cells". Cell Growth & Differentiation. 13 (1): 13–18. PMID 11801527.
24. ^ Castellino AM, Parker GJ, Boronenkov IV, Anderson RA, Chao MV (February 1997). "A novel interaction between the juxtamembrane region of the p55 tumor necrosis factor receptor and phosphatidylinositol-4-phosphate 5-kinase". The Journal of Biological Chemistry. 272 (9): 5861–5870. doi:10.1074/jbc.272.9.5861. PMID 9038203.
25. ^ Boldin MP, Mett IL, Wallach D (June 1995). "A protein related to a proteasomal subunit binds to the intracellular domain of the p55 TNF receptor upstream to its 'death domain'". FEBS Letters. 367 (1): 39–44. Bibcode:1995FEBSL.367...39B. doi:10.1016/0014-5793(95)00534-G. PMID 7601280. S2CID 21442471.
26. ^ Dunbar JD, Song HY, Guo D, Wu LW, Donner DB (May 1997). "Two-hybrid cloning of a gene encoding TNF receptor-associated protein 2, a protein that interacts with the intracellular domain of the type 1 TNF receptor: identity with subunit 2 of the 26S protease". Journal of Immunology. 158 (9): 4252–4259. doi:10.4049/jimmunol.158.9.4252. PMID 9126987.
27. ^ ^{a b c} Hsu H, Huang J, Shu HB, Baichwal V, Goeddel DV (April 1996). "TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex". Immunity. 4 (4): 387–396. doi:10.1016/S1074-7613(00)80252-6. PMID 8612133.
28. ^ Kim JW, Choi EJ, Joe CO (September 2000). "Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP". Oncogene. 19 (39): 4491–4499. doi:10.1038/sj.onc.1203796. PMID 11002422.
29. ^ Duan H, Dixit VM (January 1997). "RAIDD is a new 'death' adaptor molecule". Nature. 385 (6611): 86–89. Bibcode:1997Natur.385...86D. doi:10.1038/385086a0. hdl:2027.42/62739. PMID 8985253. S2CID 4317538.
30. ^ ^{a b} Blankenship JW, Varfolomeev E, Goncharov T, Fedorova AV, Kirkpatrick DS, Izrael-Tomasevic A, et al. (January 2009). "Ubiquitin binding modulates IAP antagonist-stimulated proteasomal degradation of c-IAP1 and c-IAP2(1)". The Biochemical Journal. 417 (1): 149–160. doi:10.1042/BJ20081885. PMID 18939944.
31. ^ Newton K, Matsumoto ML, Wertz IE, Kirkpatrick DS, Lill JR, Tan J, et al. (August 2008). "Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies". Cell. 134 (4): 668–678. doi:10.1016/j.cell.2008.07.039. PMID 18724939. S2CID 3955385.
32. ^ Varfolomeev E, Goncharov T, Fedorova AV, Dynek JN, Zobel K, Deshayes K, et al. (September 2008). "c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation". The Journal of Biological Chemistry. 283 (36): 24295–24299. doi:10.1074/jbc.C800128200. PMC 3259840. PMID 18621737.
33. ^ Liou ML, Liou HC (April 1999). "The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis". The Journal of Biological Chemistry. 274 (15): 10145–10153. doi:10.1074/jbc.274.15.10145. PMID 10187798.
34. ^ Okura T, Gong L, Kamitani T, Wada T, Okura I, Wei CF, et al. (November 1996). "Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin". Journal of Immunology. 157 (10): 4277–4281. doi:10.4049/jimmunol.157.10.4277. PMID 8906799.
35. ^ ^{a b} Shu HB, Takeuchi M, Goeddel DV (November 1996). "The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex". Proceedings of the National Academy of Sciences of the United States of America. 93 (24): 13973–13978. Bibcode:1996PNAS...9313973S. doi:10.1073/pnas.93.24.13973. PMC 19479. PMID 8943045.
36. ^ Schütze S, Machleidt T, Adam D, Schwandner R, Wiegmann K, Kruse ML, et al. (April 1999). "Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling". The Journal of Biological Chemistry. 274 (15): 10203–10212. doi:10.1074/jbc.274.15.10203. PMID 10187805.
37. ^ Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, et al. (April 1997). "The receptor for the cytotoxic ligand TRAIL". Science. 276 (5309): 111–113. doi:10.1126/science.276.5309.111. PMID 9082980. S2CID 19984057.
38. ^ Soond SM, Terry JL, Colbert JD, Riches DW (November 2003). "TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB". Molecular and Cellular Biology. 23 (22): 8334–8344. doi:10.1128/MCB.23.22.8334-8344.2003. PMC 262424. PMID 14585990.
39. ^ Bouwmeester T, Bauch A, Ruffner H, Angrand PO, Bergamini G, Croughton K, et al. (February 2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nature Cell Biology. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
40. ^ Barnhart BC, Peter ME (July 2003). "The TNF receptor 1: a split personality complex". Cell. 114 (2): 148–150. doi:10.1016/s0092-8674(03)00561-0. PMID 12887914. S2CID 11551587.
41. ^ Saltzman A, Searfoss G, Marcireau C, Stone M, Ressner R, Munro R, et al. (April 1998). "hUBC9 associates with MEKK1 and type I TNF-alpha receptor and stimulates NFkappaB activity". FEBS Letters. 425 (3): 431–435. Bibcode:1998FEBSL.425..431S. doi:10.1016/S0014-5793(98)00287-7. PMID 9563508. S2CID 84816080.

Further reading

• Rath PC, Aggarwal BB (November 1999). "TNF-induced signaling in apoptosis". Journal of Clinical Immunology. 19 (6): 350–364. doi:10.1023/A:1020546615229. PMID 10634209. S2CID 23194856.
• Chen G, Goeddel DV (May 2002). "TNF-R1 signaling: a beautiful pathway". Science. 296 (5573): 1634–1635. Bibcode:2002Sci...296.1634C. doi:10.1126/science.1071924. PMID 12040173. S2CID 25321662.
• Kollias G, Kontoyiannis D (2003). "Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments". Cytokine & Growth Factor Reviews. 13 (4–5): 315–321. doi:10.1016/S1359-6101(02)00019-9. PMID 12220546.
• Dodé C, Cuisset L, Delpech M, Grateau G (2003). "TNFRSF1A-associated periodic syndrome (TRAPS), Muckle-Wells syndrome (MWS) and renal amyloidosis". Journal of Nephrology. 16 (3): 435–437. PMID 12832748.
• Stojanov S, McDermott MF (October 2005). "The tumour necrosis factor receptor-associated periodic syndrome: current concepts". Expert Reviews in Molecular Medicine. 7 (22): 1–18. doi:10.1017/S1462399405009749. PMID 16216134. S2CID 35803989.
• Rezaei N (November 2006). "TNF-receptor-associated periodic syndrome (TRAPS): an autosomal dominant multisystem disorder". Clinical Rheumatology. 25 (6): 773–777. doi:10.1007/s10067-005-0198-6. PMID 16447098. S2CID 41808394.

External links