WNT7A |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | WNT7A, Wnt family member 7A, Wnt-7a |
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External IDs | OMIM: 601570; MGI: 98961; HomoloGene: 20969; GeneCards: WNT7A; OMA:WNT7A - orthologs |
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Gene location (Human) |
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![Chromosome 3 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/3/39/Ideogram_human_chromosome_3.svg/300px-Ideogram_human_chromosome_3.svg.png) | Chr. | Chromosome 3 (human)[1] |
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| Band | 3p25.1 | Start | 13,816,258 bp[1] |
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End | 13,880,071 bp[1] |
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Gene location (Mouse) |
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![Chromosome 6 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/c/c0/Ideogram_house_mouse_chromosome_6.svg/260px-Ideogram_house_mouse_chromosome_6.svg.png) | Chr. | Chromosome 6 (mouse)[2] |
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| Band | 6 D1|6 40.45 cM | Start | 91,340,963 bp[2] |
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End | 91,388,345 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - ventricular zone
- ganglionic eminence
- prefrontal cortex
- gonad
- right frontal lobe
- cingulate gyrus
- anterior cingulate cortex
- amygdala
- right lung
- Brodmann area 9
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| Top expressed in | - surface ectoderm
- set of lens fibers
- corneal epithelium
- epithelium of lens
- paramesonephric duct
- corneal endothelium
- epithelium of vagina
- medial ganglionic eminence
- ventricular zone
- Rostral migratory stream
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/0/01/PBB_GE_WNT7A_210248_at_fs.png/250px-PBB_GE_WNT7A_210248_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - receptor ligand activity
- cytokine activity
- frizzled binding
- protein binding
- signaling receptor binding
| Cellular component | - endocytic vesicle membrane
- endoplasmic reticulum lumen
- plasma membrane
- extracellular fluid
- extracellular region
- cell surface
- Golgi lumen
- extracellular exosome
- presynapse
- synapse
| Biological process | - positive regulation of synapse assembly
- cellular response to transforming growth factor beta stimulus
- excitatory synapse assembly
- roof of mouth development
- non-canonical Wnt signaling pathway
- cell fate commitment
- response to estradiol
- positive regulation of epithelial cell proliferation involved in wound healing
- chondrocyte differentiation
- axonogenesis
- somatic stem cell population maintenance
- uterus morphogenesis
- stem cell development
- positive regulation of canonical Wnt signaling pathway
- negative regulation of neurogenesis
- synapse organization
- somatic stem cell division
- embryonic digit morphogenesis
- positive regulation of protein localization to synapse
- embryonic axis specification
- sex differentiation
- negative regulation of apoptotic process
- positive regulation of JNK cascade
- wound healing
- Wnt signaling pathway involved in wound healing, spreading of epidermal cells
- response to estrogen
- limb development
- positive regulation of endothelial cell migration
- positive regulation of transcription, DNA-templated
- multicellular organism development
- regulation of axonogenesis
- dendritic spine morphogenesis
- synaptic vesicle recycling
- uterus development
- regulation of axon diameter
- skeletal muscle satellite cell activation
- positive regulation of gene expression
- cartilage development
- regulation of cell population proliferation
- embryonic limb morphogenesis
- skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration
- angiogenesis
- oviduct development
- establishment of cell polarity
- central nervous system vasculogenesis
- positive regulation of excitatory postsynaptic potential
- positive regulation of cell population proliferation
- canonical Wnt signaling pathway
- synapse assembly
- positive regulation of excitatory synapse assembly
- dorsal/ventral pattern formation
- cell proliferation in forebrain
- embryonic forelimb morphogenesis
- neurotransmitter secretion
- cartilage condensation
- lens fiber cell development
- cerebellar granule cell differentiation
- positive regulation of transcription by RNA polymerase II
- embryonic hindlimb morphogenesis
- Wnt signaling pathway
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 3: 13.82 – 13.88 Mb | Chr 6: 91.34 – 91.39 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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