KIF14 |
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Visualisation de la protéine Cristallisée KIF14 |
Structures disponibles |
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PDB | Recherche d'orthologue: PDBe RCSB |
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Identifiants |
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Aliases | KIF14, kinesin family 14 |
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IDs externes | OMIM: 611279 MGI: 1098226 HomoloGene: 8916 GeneCards: KIF14 |
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Position du gène (Homme) |
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| Chr. | Chromosome 1 humain[1] |
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| Locus | 1q32.1 | Début | 200,551,497 bp[1] |
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Fin | 200,620,751 bp[1] |
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Position du gène (Souris) |
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| Chr. | Chromosome 1 (souris)[2] |
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| Locus | 1 E4|1 59.8 cM | Début | 136,394,081 bp[2] |
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Fin | 136,459,249 bp[2] |
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Expression génétique |
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Bgee | Humain | Souris (orthologue) |
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Fortement exprimé dans | - secondary oocyte
- os spongieux
- gonade
- ventricular zone
- buccal mucosa cell
- testicule
- embryon
- moelle osseuse
- thymus
- éminence ganglionnaire
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| Fortement exprimé dans | - zygote
- tail of embryo
- tubercule génital
- secondary oocyte
- spermatocyte
- ventricular zone
- spermatide
- Vésicule vitelline
- blastocyste
- embryon
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| Plus de données d'expression de référence |
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BioGPS | | Plus de données d'expression de référence |
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Gene Ontology |
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Fonction moléculaire | - tubulin binding
- liaison nucléotide
- protein kinase binding
- plus-end-directed microtubule motor activity
- PDZ domain binding
- microtubule motor activity
- microtubule binding
- liaison ATP
- liaison protéique
- activité ATPase
| Composant cellulaire | - fuseau mitotique
- cytoplasme
- Kinésine
- noyau
- membrane
- midbody
- microtubule
- membrane plasmique
- spindle midzone
- cytosquelette
- cytosol
- Flemming body
| Processus biologique | - negative regulation of integrin activation
- développement du cortex cérébral
- negative regulation of apoptotic process
- SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
- regulation of neuron apoptotic process
- hippocampus development
- regulation of cell growth
- division cellulaire
- substrate adhesion-dependent cell spreading
- regulation of G1/S transition of mitotic cell cycle
- cell proliferation in forebrain
- regulation of G2/M transition of mitotic cell cycle
- cerebellar granular layer structural organization
- olfactory bulb development
- microtubule depolymerization
- proteasome-mediated ubiquitin-dependent protein catabolic process
- cerebellar Purkinje cell layer structural organization
- regulation of myelination
- positive regulation of cell population proliferation
- regulation of Rap protein signal transduction
- cerebellar cortex development
- positive regulation of cytokinesis
- negative regulation of neuron apoptotic process
- establishment of protein localization
- regulation of cell migration
- mitotic metaphase plate congression
- regulation of cell maturation
- microtubule-based movement
- activation of protein kinase activity
- regulation of cell adhesion
| Sources:Amigo / QuickGO |
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Orthologues |
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Espèces | Homme | Souris |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protéine) | | |
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Localisation (UCSC) | Chr 1: 200.55 – 200.62 Mb | Chr 1: 136.39 – 136.46 Mb |
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Publication PubMed | [3] | [4] |
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Wikidata |
Voir/Editer Humain | Voir/Editer Souris |
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