• calcium ion binding • 金属イオン結合 • cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication • cell adhesion molecule binding
^Arnemann J, Spurr NK, Magee AI, Buxton RS (July 1992). “The human gene (DSG2) coding for HDGC, a second member of the desmoglein subfamily of the desmosomal cadherins, is, like DSG1 coding for desmoglein DGI, assigned to chromosome 18”. Genomics13 (2): 484-486. doi:10.1016/0888-7543(92)90280-6. PMID 1612610.
^Chitaev NA, Troyanovsky SM (1997). “Direct Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion”. J. Cell Biol.138 (1): 193-201. PMC 2139935. PMID 9214392. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139935/.
^Bannon LJ, Cabrera BL, Stack MS, Green KJ (2001). “Isoform-specific differences in the size of desmosomal cadherin/catenin complexes”. J. Invest. Dermatol.117 (5): 1302-1306. doi:10.1046/j.1523-1747.2001.01512.x. PMID 11710948.
^Nieset JE, Sacco-Bubulya PA, Sadler TM, Johnson KR, Wheelock MJ, Jk3rd (2000). “The amino- and carboxyl-terminal tails of (beta)-catenin reduce its affinity for desmoglein 2”. J. Cell. Sci.113 ( Pt 10): 1737-1745. PMID 10769205.
^Ozawa M, Terada H, Pedraza C (1995). “The fourth armadillo repeat of plakoglobin (gamma-catenin) is required for its high affinity binding to the cytoplasmic domains of E-cadherin and desmosomal cadherin Dsg2, and the tumor suppressor APC protein”. J. Biochem.118 (5): 1077-1082. PMID 8749329.
^Bonne S, Gilbert B, Hatzfeld M, Chen X, Green KJ, van Roy F (April 2003). “Defining desmosomal plakophilin-3 interactions”. J. Cell Biol.161 (2): 403-416. doi:10.1083/jcb.200303036. PMC 2172904. PMID 12707304. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172904/.
^Awad MM, Dalal D, Cho E, Amat-Alarcon N, James C, Tichnell C, Tucker A, Russell SD, Bluemke DA, Dietz HC, Calkins H, Judge DP (July 2006). “DSG2 mutations contribute to arrhythmogenic right ventricular dysplasia/cardiomyopathy”. Am J Hum Genet79 (1): 136-142. PMC 1474134. PMID 16773573. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1474134/.
^Yashiro M, Nishioka N, Hirakawa K (Sep 2006). “Decreased expression of the adhesion molecule desmoglein-2 is associated with diffuse-type gastric carcinoma”. Eur J Cancer42 (14): 2397-2403. PMID 16890424.
^Ramani VC, Hennings L, Haun RS (Dec 2008). “Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer”. BMC Cancer8: 373-. doi:10.1186/1471-2407-8-373. PMC 2628383. PMID 19091121. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628383/.
参考文献
Amagai M, Stanley JR (Mar 2012). “Desmoglein as a target in skin disease and beyond”. J Invest Dermatol132 (3 Pt 2): 776-784. doi:10.1038/jid.2011.390.. PMC 3279627. PMID 22189787. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3279627/.(英語)
AP Kowalczyk, KJ Green (1996). “Chapter10. The desmosome: a comparison system for adhesion and intermediate filament attachment”. In WJ Nelson. Membrane Protein-Cytoskeleton Interactions. Academic Press. p. 187-210. ISBN 012-153343-3. https://books.google.co.jp/books?id=yAcvo9BgyvUC&pg=PA196&lpg=PA196&dq=desmoglein+IA&source=bl&ots=tRgyIrFi9b&sig=3mkfIIGFN1uT8fvTbVcq9av8ouY&hl=ja&sa=X&ei=E88-UpDGB6ejige8_YCQCw&ved=0CEcQ6AEwBA#v=onepage&q=desmoglein%20IA&f=false(英語)
Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Raff, Martin; Roberts, Keith; Walter, Peter (2002). “anchoring junction”. Molecular Biology of the Cell (4th ed.). New York: Garland Science. ISBN 0-8153-3218-1. http://www.ncbi.nlm.nih.gov/books/NBK26857(英語)
関連英文論文
Koch PJ, Goldschmidt MD, Walsh MJ, et al. (1991). “Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.”. Eur. J. Cell Biol.55 (2): 200-208. PMID 1935985.
Simrak D, Cowley CM, Buxton RS, Arnemann J (1995). “Tandem arrangement of the closely linked desmoglein genes on human chromosome 18.”. Genomics25 (2): 591-594. doi:10.1016/0888-7543(95)80067-V. PMID 7790000.
Schafer S, Koch PJ, Franke WW (1994). “Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins.”. Exp. Cell Res.211 (2): 391-399. doi:10.1006/excr.1994.1103. PMID 8143788.
Schafer S, Stumpp S, Franke WW (1996). “Immunological identification and characterization of the desmosomal cadherin Dsg2 in coupled and uncoupled epithelial cells and in human tissues.”. Differentiation60 (2): 99-108. doi:10.1046/j.1432-0436.1996.6020099.x. PMID 8641550.
Ozawa M, Terada H, Pedraza C (1997). “The fourth armadillo repeat of plakoglobin (gamma-catenin) is required for its high affinity binding to the cytoplasmic domains of E-cadherin and desmosomal cadherin Dsg2, and the tumor suppressor APC protein.”. J. Biochem.118 (5): 1077-1082. PMID 8749329.
Chitaev NA, Troyanovsky SM (1997). “Direct Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion.”. J. Cell Biol.138 (1): 193-201. doi:10.1083/jcb.138.1.193. PMC 2139935. PMID 9214392. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139935/.
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Krunic AL, Garrod DR, Madani S, et al. (1998). “Immunohistochemical staining for desmogleins 1 and 2 in keratinocytic neoplasms with squamous phenotype: actinic keratosis, keratoacanthoma and squamous cell carcinoma of the skin.”. Br. J. Cancer77 (8): 1275-1279. doi:10.1038/bjc.1998.213. PMC 2150164. PMID 9579833. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2150164/.
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Wahl JK3rd , Nieset JE, Sacco-Bubulya PA, et al. (2000). “The amino- and carboxyl-terminal tails of (beta)-catenin reduce its affinity for desmoglein 2.”. J. Cell. Sci.113 (10): 1737-1745. PMID 10769205.
Bannon LJ, Cabrera BL, Stack MS, Green KJ (2001). “Isoform-specific differences in the size of desmosomal cadherin/catenin complexes.”. J. Invest. Dermatol.117 (5): 1302-1306. doi:10.1046/j.1523-1747.2001.01512.x. PMID 11710948.
Chen X, Bonne S, Hatzfeld M, et al. (2002). “Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling.”. J. Biol. Chem.277 (12): 10512-19522. doi:10.1074/jbc.M108765200. PMID 11790773.
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A.99 (26): 16899-16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139241/.
Bonne S, Gilbert B, Hatzfeld M, et al. (2003). “Defining desmosomal plakophilin-3 interactions.”. J. Cell Biol.161 (2): 403-416. doi:10.1083/jcb.200303036. PMC 2172904. PMID 12707304. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172904/.
Zhang H, Li XJ, Martin DB, Aebersold R (2003). “Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.”. Nat. Biotechnol.21 (6): 660-666. doi:10.1038/nbt827. PMID 12754519.
Wu H, Stanley JR, Cotsarelis G (2003). “Desmoglein isotype expression in the hair follicle and its cysts correlates with type of keratinization and degree of differentiation.”. J. Invest. Dermatol.120 (6): 1052-1057. doi:10.1046/j.1523-1747.2003.12234.x. PMID 12787134.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). “Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.”. Genome Res.14 (9): 1711-1718. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC515316/.
Amanchy R, Kalume DE, Iwahori A, et al. (2006). “Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC).”. J. Proteome Res.4 (5): 1661-1671. doi:10.1021/pr050134h. PMID 16212419.
GeneReviews/NCBI/NIH/UW entry on Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy, Autosomal Dominant(英語)
DSG2 (desmoglein 2)(英語)
http://www.ncbi.nlm.nih.gov/omim/604772,605676,601214,107970,125645,125647,125671,173325,180902,190230,600996,602086,602087,602861,604400,604401,607450,609040,609160,610193,610476,611528,612048,107970,125645,125647,125671,173325,180902,190230,600996,602086,602087,602861,604400,604401,607450,609040,609160,610193,610476,611528,612048 OMIM entries on Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy, Autosomal Dominant](英語)