RUNX1 |
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PDBに登録されている構造 |
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PDB | オルソログ検索: RCSB PDBe PDBj |
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PDBのIDコード一覧 |
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1CMO, 1CO1, 1E50, 1H9D, 1LJM |
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識別子 |
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記号 | RUNX1, AML1, AML1-EVI-1, AMLCR1, CBF2alpha, CBFA2, EVI-1, PEBP2aB, PEBP2alpha, runt related transcription factor 1, RUNX family transcription factor 1 |
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外部ID | OMIM: 151385 MGI: 99852 HomoloGene: 1331 GeneCards: RUNX1 |
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遺伝子の位置 (ヒト) |
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| 染色体 | 21番染色体 (ヒト)[1] |
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| バンド | データ無し | 開始点 | 34,787,801 bp[1] |
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終点 | 36,004,667 bp[1] |
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遺伝子の位置 (マウス) |
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| 染色体 | 16番染色体 (マウス)[2] |
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| バンド | データ無し | 開始点 | 92,398,354 bp[2] |
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終点 | 92,623,037 bp[2] |
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遺伝子オントロジー |
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分子機能 | • DNA結合 • calcium ion binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • protein homodimerization activity • DNA-binding transcription factor activity • DNA-binding transcription activator activity, RNA polymerase II-specific • 転写因子結合 • 血漿タンパク結合 • protein heterodimerization activity • ATP binding • DNA-binding transcription factor activity, RNA polymerase II-specific • RNA polymerase II cis-regulatory region sequence-specific DNA binding
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細胞の構成要素 | • intracellular membrane-bounded organelle • 細胞核 • 細胞質基質 • 核質 • core-binding factor complex
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生物学的プロセス | • peripheral nervous system neuron development • myeloid cell differentiation • regulation of transcription, DNA-templated • chondrocyte differentiation • 骨形成 • negative regulation of granulocyte differentiation • hematopoietic stem cell proliferation • transcription, DNA-templated • positive regulation of angiogenesis • positive regulation of transcription, DNA-templated • positive regulation of interleukin-2 production • positive regulation of granulocyte differentiation • positive regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • regulation of cytokine-mediated signaling pathway • regulation of Wnt signaling pathway • regulation of intracellular estrogen receptor signaling pathway • regulation of regulatory T cell differentiation • regulation of keratinocyte differentiation • regulation of myeloid cell differentiation • regulation of megakaryocyte differentiation • regulation of B cell receptor signaling pathway • regulation of hematopoietic stem cell differentiation • regulation of bicellular tight junction assembly • 造血 • negative regulation of transcription by RNA polymerase II • negative regulation of CD4-positive, alpha-beta T cell differentiation • positive regulation of CD8-positive, alpha-beta T cell differentiation • 遺伝子発現の負の調節 • neuron differentiation
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出典:Amigo / QuickGO |
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オルソログ |
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種 | ヒト | マウス |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | |
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NM_001001890 NM_001122607 NM_001754 |
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NM_001111021 NM_001111022 NM_001111023 NM_009821 |
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RefSeq (タンパク質) | |
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NP_001001890 NP_001116079 NP_001745 |
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場所 (UCSC) | Chr 21: 34.79 – 36 Mb | Chr 21: 92.4 – 92.62 Mb |
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PubMed検索 | [3] | [4] |
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ウィキデータ |
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