Benziltiourasil
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Data klinikal | |
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AHFS/Drugs.com | International Drug Names |
Kaedah pemberian | Mulut |
Kod ATC |
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Data farmakokinetik | |
Perkumuhan | Buah pinggang |
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Nombor CAS |
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ChemSpider |
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ChEMBL |
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CompTox Dashboard (EPA) |
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ECHA InfoCard | 100.026.106 ![]() |
Data kimia dan fizikal | |
Formula | C11H10N2OS |
Jisim molar | 218.27 g·mol−1 |
Model 3D (JSmol) |
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Benziltiourasil (BTU) ialah sebuah penyediaan antitiroid. Ia merupakan sejenis tioamida, serupa dengan propiltiourasil.
Kesan sampingan
Benziltiourasil telah dikaitkan dengan kesan sampingan, terutamanya vaskulitis dan seterusnya glomerulonefritis positif ANCA, serta kes-kes terpencil kerosakan peparu.[1][2][3][4]
Rujukan
- ^ Tieulie N, Huong DL, Andreu M, dll. (2002). "[ANCA associated glomerulonephritis related to benzylthiouracil]". Rev Méd Interne (dalam bahasa French). 23 (10): 853–6. doi:10.1016/S0248-8663(02)00694-X. PMID 12428489.CS1 maint: unrecognized language (link)
- ^ Kaaroud H, Khiari K, Ben Moussa F, Barbouch S, Boussema E, Ben Maïz H (2002). "[Vasculitis with renal and pulmonary involvement in a patient receiving benzylthiouracil for Graves disease]". Rev Méd Interne (dalam bahasa French). 23 (10): 857–61. doi:10.1016/S0248-8663(02)00704-X. PMID 12428490.CS1 maint: unrecognized language (link)
- ^ Braham A, Houman MH, Rais L, Ben Gborbel I, Lamloum M, Miled M (2004). "[Benzylthiouracil induced ANCA-positive vasculitis]". Presse Médicale (dalam bahasa French). 33 (19 Pt 1): 1331–3. doi:10.1016/S0755-4982(04)98919-1. PMID 15615240.CS1 maint: unrecognized language (link)
- ^ Thabet F, Sghiri R, Tabarki B, Ghedira I, Yacoub M, Essoussi AS (2006). "ANCA-associated diffuse alveolar hemorrhage due to benzylthiouracil". Eur J Pediatr. 165 (7): 435–6. doi:10.1007/s00431-005-0053-4. PMID 16622664.
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