Amin dehidrogenaza
| Amin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.4.99.3 | ||||||||
| CAS broj | 60496-14-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Amin dehidrogenaza (EC 1.4.99.3, metilamin dehidrogenaza, primarni-amin dehidrogenaza, amin: (akceptor) oksidoreduktaza (deaminacija), primarni-amin:(akceptor) oksidoreduktaza (deaminacija)) je enzim sa sistematskim imenom primarni-amin:akceptor oksidoreduktaza (deaminacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- RCH2NH2 + H2O + akceptor RCHO + NH3 + redukovani akceptor
Ovaj enzim je hinoprotein.
Reference
- ↑ De Beer, R., Duine, J.A., Frank, J., Jr. and Large, P.J. (1980). „The prosthetic group of methylamine dehydrogenase from Pseudomonas AM1: evidence for a quinone structure”. Biochim. Biophys. Acta 622: 370-374. PMID 6246962.
- ↑ Eady, R.R. and Large, P.J. (1968). „Purification and properties of an amine dehydrogenase from Pseudomonas AM1 and its role in growth on methylamine”. Biochem. J. 106: 245-255. PMID 4388687.
- ↑ Eady, R.R. and Large, P.J. (1971). „Microbial oxidation of amines. Spectral and kinetic properties of the primary amine dehydrogenase of Pseudomonas AM1”. Biochem. J. 123: 757-771. PMID 5124384.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH Amine+dehydrogenase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
