• metabolički proces energijske rezerve • GTP katabolički proces • prenos signala • signalni put adenilat ciklazom aktiviranog dopaminskog receptora • signalni put fosfolipazom C aktivating G protein spregnutog receptora
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta
Čovek
Miš
Entrez
n/a
14688
Ensembl
ENSG00000078369
ENSMUSG00000029064
UniProt
P62873
P62874
RefSeq (mRNA)
NM_002074.3
NM_001160016.1
RefSeq (protein)
NP_002065.1
NP_001153488.1
Lokacija (UCSC)
Chr 1: 1.72 - 1.82 Mb
Chr 4: 154.87 - 154.93 Mb
PubMed pretraga
n/a
[1]
Vezujući protein guaninskog nukleotida G(I)/G(S)/G(T) podjedinica beta-1 je protein koji je kod ljudi kodiran GNB1 genom.[1]
Heterotrimerni vezujući protein guaninskog nukleotida (G proteina), koji integrišu signale između receptora i efektorskih proteina, se sastoje od alfa, beta, i gama podjedinice. Te podjedinice su kodirane familijama srodnih gena. Ovaj gen kodira beta podjedinicu, koja je regulator alfa podjedinica, kao i pojedinih receptora i efektora. Ovaj gen koristi alternativne signale poliadenilacije.[1]
↑Ray, K; Kunsch C, Bonner L M, Robishaw J D (September 1995). „Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits”. J. Biol. Chem. (UNITED STATES) 270 (37): 21765–71. DOI:10.1074/jbc.270.37.21765. ISSN 0021-9258. PMID 7665596.
↑Yan, K; Kalyanaraman V, Gautam N (March 1996). „Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families”. J. Biol. Chem. (UNITED STATES) 271 (12): 7141–6. DOI:10.1074/jbc.271.12.7141. ISSN 0021-9258. PMID 8636150.
Literatura
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