Glukoza-6-fosfataza
Glukoza-6-fosfataza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.1.3.9 | ||||||||
CAS broj | 9001-39-2 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Glukoza-6-fosfataza (EC 3.1.3.9, glukoza 6-fosfatna fosfataza) je enzim sa sistematskim imenom D-glukoza-6-fosfat fosfohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-glukoza 6-fosfat + H2O D-glukoza + fosfat
Ovaj enzim je široko rasprostranjen u životinjskim tkivima.
Reference
- ↑ Anchors, J.M. and Karnovsky, N.L. (1975). „Purification of cerebral glucose-6-phosphatase. An enzyme involved in sleep”. J. Biol. Chem. 250: 6408-6416. PMID 169241.
- ↑ Colilla, W., Jorgenson, R.A. and Nordlie, R.C. (1975). „Mammalian carbamyl phosphate : glucose phosphotransferase and glucose-6-phosphate phosphohydrolase: extended tissue distribution”. Biochim. Biophys. Acta 377: 117-117. PMID 164220.
- ↑ Nordlie, R.C. (1971). „Glucose-6-phosphatase, hydrolytic and synthetic activities”. u: Boyer, P.D.. The Enzymes. 4 (3rd izd.). New York: Academic Press. str. 543-610.
- ↑ Nordlie, R.C. (1974). „Metabolic regulation by multifunctional glucose-6-phosphatase”. Curr. Top. Cell. Regul. 8: 33-33. PMID 4370737.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Nordlie, R.C. (1971). „Glucose-6-phosphatase, hydrolytic and synthetic activities”. u: Boyer, P.D.. The Enzymes. 4 (3rd izd.). New York: Academic Press. str. 543-610.
Spoljašnje veze
- MeSH Glucose-6-phosphatase
- p
- r
- u
Holinesteraza (Acetilholinesteraza, Butirilholinesteraza) • Pektinesteraza • 6-fosfoglukonolaktonaza • PAF acetilhidrolaza
Lipaza (Zavisna od žučnih soli, Gastrična/Lingvalna, Pankreasna, Lizozomalna, Hormon-sensitivna, Endotelna, Hepatička, Lipoproteinska, Monoacilglicerolna, Diacilglicerolna)
Fosfolipaza (A1, A2, B)Tioesteraza palmitoil proteina • Ubikvitin karboksilni-terminal hidrolaza L1
Alkalna fosfataza (ALPI, ALPL, ALPP) • Kiselinska fosfataza (Prostatična)/Tartrat-otporna kiselinska fosfataza/Fosfataze purpurne kiseline • Nukleotidaza • Glukoza 6-fosfataza • Fruktoza 1,6-bisfosfataza •
Kalcineurin • Fosfoproteinska fosfataza (PP2A) • OCRL • Piruvat dehidrogenazna fosfataza • Fruktoza 6-P,2-kinaza:fruktoza 2,6-bisfosfataza •PTEN • Fitaza • Inozitol-fosfat fosfataza (IMPA1)
Autotaksin • Fosfolipaza (C, D) • Sfingomijelin fosfodiesteraza (1) • PDE1 • PDE2 • PDE3 • PDE4A/PDE4B • PDE5 • Lecitinaza (Clostridium perfringens alfa toksin) • Fosfodiesteraza cikličnih nukleotida
arilsulfataza (Arilsulfataza A, Arilsulfataza B, Arilsulfataza E, Steroidna sulfataza) • Galaktozamine-6 sulfataza • Iduronat-2-sulfataza • N-acetilglukosamin-6-sulfataza
deoksiribonukleazu i
ribonukleazu)
3.1.11-16: Eksonukleaza |
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3.1.21-31: Endonukleaza |
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B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6