Magnezijumska helataza
| Magnezijumska helataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Identifikatori | |||||||||
| EC broj | 6.6.1.1 | ||||||||
| CAS broj | 9074-88-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Magnezijumska helataza (EC 6.6.1.1, protoporfirin IX magnezijum-helataza, protoporfirin IX Mg-helataza, magnezijum-protoporfirin IX helataza, magnezijum-protoporfirin helataza, magnezijum-helataza, Mg-helataza, Mg-protoporfirin IX magnezio-lijaza) je enzim sa sistematskim imenom Mg-protoporfirin IX magnezijum-lijaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + protoporfirin IX + Mg2+ + H2O ADP + fosfat + Mg-protoporfirin IX + 2 H+
Ovaj enzim posreduje prvi korak u biosintezi hlorofila.
Reference
- ↑ Walker, C.J. and Weinstein, J.D. (1991). „In vitro assay of the chlorophyll biosynthetic enzyme Mg-chelatase: resolution of the activity into soluble and membrane-bound fractions”. Proc. Natl. Acad. Sci. USA 88: 5789-5793. PMID 11607197.
- ↑ Walker, C.J. and Willows, R.D. (1997). „Mechanism and regulation of Mg-chelatase”. Biochem. J. 327: 321-333. PMID 9359397.
- ↑ Fodje, M.N., Hansson, A., Hansson, M., Olsen, J.G., Gough, S., Willows, R.D. and Al-Karadaghi, S. (2001). „Interplay between an AAA module and an integrin I domain may regulate the function of magnesium chelatase”. J. Mol. Biol. 311: 111-122. PMID 11469861.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Magnesium+chelatase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
