Piretroidna hidrolaza

Piretroidna hidrolaza
Identifikatori
EC broj 3.1.1.88
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC articles
PubMed articles
NCBI Protein search

Piretroidna hidrolaza (EC 3.1.1.88, piretroid-hidrolizirajuća karboksilesteraza, piretroid-hidrolizujuća esteraza, piretroid-hidrolizirajuća esteraza, piretroid-selektivna esteraza, enzim razgradnje pirethroida, permetrinaza, PytH, EstP) je enzim sa sistematskim imenom pirethroid-estar hidrolaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

trans-permetrin + H2O ⇌ {\displaystyle \rightleftharpoons } (3-fenoksifenil)metanol + (1S,3R)-3-(2,2-dihloroetenil)-2,2-dimetilciklopropankarboksilat

Ovaj enzim učestvuje u degradaciji piretroidnih pesticida.

Reference

  1. ↑ Wang, B.Z., Guo, P., Hang, B.J., Li, L., He, J. and Li, S.P. (2009). „Cloning of a novel pyrethroid-hydrolyzing carboxylesterase gene from Sphingobium sp. strain JZ-1 and characterization of the gene product”. Appl. Environ. Microbiol. 75: 5496-5500. PMID 19581484. 
  2. ↑ Wu, P.C., Liu, Y.H., Wang, Z.Y., Zhang, X.Y., Li, H., Liang, W.Q., Luo, N., Hu, J.M., Lu, J.Q., Luan, T.G. and Cao, L.X. (2006). „Molecular cloning, purification, and biochemical characterization of a novel pyrethroid-hydrolyzing esterase from Klebsiella sp. strain ZD112”. J. Agric. Food Chem. 54: 836-842. PMID 16448191. 
  3. ↑ Liang, W.Q., Wang, Z.Y., Li, H., Wu, P.C., Hu, J.M., Luo, N., Cao, L.X. and Liu, Y.H. (2005). „Purification and characterization of a novel pyrethroid hydrolase from Aspergillus niger ZD11”. J. Agric. Food Chem. 53: 7415-7420. PMID 16159167. 
  4. ↑ Stok, J.E., Huang, H., Jones, P.D., Wheelock, C.E., Morisseau, C. and Hammock, B.D. (2004). „Identification, expression, and purification of a pyrethroid-hydrolyzing carboxylesterase from mouse liver microsomes”. J. Biol. Chem. 279: 29863-29869. PMID 15123619. 
  5. ↑ Maloney, S.E., Maule, A. and Smith, A.R. (1993). „Purification and preliminary characterization of permethrinase from a pyrethroid-transforming strain of Bacillus cereus”. Appl. Environ. Microbiol. 59: 2007-2013. PMID 8357241. 
  6. ↑ Guo, P., Wang, B., Hang, B., Li, L., Ali, W., He, J. and Li, S. (2009). „Pyrethroid-degrading Sphingobium sp. JZ-2 and the purification and characterization of a novel pyrethroid hydrolase”. Int. Biodeter. Biodegrad. 63: 1107-1112. 

Literatura

  • Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
  • Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
  • Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Spoljašnje veze

  • MeSH Pyrethroid+hydrolase
  • p
  • r
  • u
TemeTipovi
EC1 Oksidoreduktaze/spisak  • EC2 Transferaze/spisak  • EC3 Hidrolaze/spisak  • EC4 Lijaze/spisak  • EC5 Izomeraze/spisak  • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6