Receptor slobodnih masnih kiselina 2
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Receptor slobodnih masnih kiselina 2 | |||||||||||
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Identifikatori | |||||||||||
Simboli | FFAR2; FFA2R; GPR43 | ||||||||||
Vanjski ID | OMIM: 603823 MGI: 2441731 HomoloGene: 128287 IUPHAR: FFA2 GeneCards: FFAR2 Gene | ||||||||||
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Pregled RNK izražavanja | |||||||||||
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podaci | |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 2867 | 233079 | |||||||||
Ensembl | ENSG00000126262 | ENSMUSG00000051314 | |||||||||
UniProt | O15552 | Q8VCK6 | |||||||||
RefSeq (mRNA) | NM_005306.2 | NM_001168509.1 | |||||||||
RefSeq (protein) | NP_005297.1 | NP_001161981.1 | |||||||||
Lokacija (UCSC) | Chr 19: 35.94 - 35.94 Mb | Chr 7: 31.6 - 31.61 Mb | |||||||||
PubMed pretraga | [1] | [2] |
Receptor slobodnih masnih kiselina 2 (FFA2) je G protein spregnuti receptor kodiran FFAR2 genom.[1]
Reference
- ↑ „Entrez Gene: FFAR2 free fatty acid receptor 2”.
Literatura
- Brown AJ, Jupe S, Briscoe CP (2005). „A family of fatty acid binding receptors.”. DNA Cell Biol. 24 (1): 54–61. DOI:10.1089/dna.2005.24.54. PMID 15684720.
- Sawzdargo M, George SR, Nguyen T, et al. (1997). „A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1.”. Biochem. Biophys. Res. Commun. 239 (2): 543–7. DOI:10.1006/bbrc.1997.7513. PMID 9344866.
- Senga T, Iwamoto S, Yoshida T, et al. (2003). „LSSIG is a novel murine leukocyte-specific GPCR that is induced by the activation of STAT3.”. Blood 101 (3): 1185–7. DOI:10.1182/blood-2002-06-1881. PMID 12393494.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Brown AJ, Goldsworthy SM, Barnes AA, et al. (2003). „The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.”. J. Biol. Chem. 278 (13): 11312–9. DOI:10.1074/jbc.M211609200. PMID 12496283.
- Nilsson NE, Kotarsky K, Owman C, Olde B (2003). „Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids.”. Biochem. Biophys. Res. Commun. 303 (4): 1047–52. DOI:10.1016/S0006-291X(03)00488-1. PMID 12684041.
- Le Poul E, Loison C, Struyf S, et al. (2003). „Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation.”. J. Biol. Chem. 278 (28): 25481–9. DOI:10.1074/jbc.M301403200. PMID 12711604.
- Grimwood J, Gordon LA, Olsen A, et al. (2004). „The DNA sequence and biology of human chromosome 19.”. Nature 428 (6982): 529–35. DOI:10.1038/nature02399. PMID 15057824.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Yonezawa T, Kobayashi Y, Obara Y (2007). „Short-chain fatty acids induce acute phosphorylation of the p38 mitogen-activated protein kinase/heat shock protein 27 pathway via GPR43 in the MCF-7 human breast cancer cell line.”. Cell. Signal. 19 (1): 185–93. DOI:10.1016/j.cellsig.2006.06.004. PMID 16887331.
Povezano
Spoljašnje veze
- „Free Fatty Acid Receptors: FFA2”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.
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Drugi | Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2) |
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glutamat / feromon
Drugi |
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Frizzled / Zaglađeni
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Zaglađeni |
B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)