Urejna karboksilaza
| Urejna karboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.4.6 | ||||||||
| CAS broj | 9058-98-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Urejna karboksilaza (EC 6.3.4.6, ureaza (ATP hidrolizacija), urejna karboksilaza (hidrolizacija), ATP-urejna amidolijaza, urejna amidolijaza, UALaza, UCA) je enzim sa sistematskim imenom ureja:karbon-dioksid ligaza (formira ADP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + ureja + HCO3- ADP + fosfat + ureja-1-karboksilat
Ovaj enzim je biotinilni protein.
Reference
- ↑ Roon, R.J. and Levenberg, B. (1970). „ATP-Urea amidolyase (ADP) (Candida utilis)”. Methods Enzymol. 17A: 317-324.
- ↑ Roon, R.J. and Levenberg, B. (1972). „Urea amidolyase. I. Properties of the enzyme from Candida utilis”. J. Biol. Chem. 247: 4107-4113. PMID 4556303.
- ↑ Sumrada, R.A. and Cooper, T.G. (1982). „Urea carboxylase and allophanate hydrolase are components of a multifunctional protein in yeast”. J. Biol. Chem. 257: 9119-9127. PMID 6124544.
- ↑ Kanamori, T., Kanou, N., Atomi, H. and Imanaka, T. (2004). „Enzymatic characterization of a prokaryotic urea carboxylase”. J. Bacteriol. 186: 2532-2539. PMID 15090492.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Urea+carboxylase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
